5-HT
Antigens, CD20
/ analysis
CD4 Antigens
/ analysis
CD8 Antigens
/ analysis
Chagas Disease
/ pathology
Enteric Nervous System
/ pathology
Humans
Immune System
/ pathology
Lymphocytes
/ metabolism
Megacolon
/ parasitology
Middle Aged
Receptors, Serotonin, 5-HT3
/ metabolism
Serotonin
Trypanosoma cruzi
/ pathogenicity
5-HT3A
Chagas disease
Enteric nervous system
Lymphocytes
Megacolon
Journal
Parasitology research
ISSN: 1432-1955
Titre abrégé: Parasitol Res
Pays: Germany
ID NLM: 8703571
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
26
03
2018
accepted:
30
01
2019
pubmed:
13
2
2019
medline:
6
5
2019
entrez:
13
2
2019
Statut:
ppublish
Résumé
Chagas disease is caused by Trypanosoma cruzi and remains one of the most neglected diseases in Latin America. One of its clinical forms is Chagas megacolon. Despite being known for more than half a century, detailed causes are still obscure. Recent evidence indicates a close relationship between the immune system and the enteric nervous system in the etiology of chagasic megacolon pathology. It is believed that low expression of the 5-HT
Identifiants
pubmed: 30747295
doi: 10.1007/s00436-019-06241-w
pii: 10.1007/s00436-019-06241-w
doi:
Substances chimiques
Antigens, CD20
0
CD4 Antigens
0
CD8 Antigens
0
HTR3E protein, human
0
Receptors, Serotonin, 5-HT3
0
Serotonin
333DO1RDJY
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1325-1329Références
Clin Chim Acta. 2009 May;403(1-2):47-55
pubmed: 19361459
Pharmacol Ther. 2010 Oct;128(1):146-69
pubmed: 20621123
Bioorg Med Chem Lett. 2012 Jan 15;22(2):1151-5
pubmed: 22189135
Minerva Endocrinol. 2011 Dec;36(4):311-24
pubmed: 22322654
Eur J Pharmacol. 2014 Jan 5;722:13-25
pubmed: 24189639
Colorectal Dis. 2015 Mar;17(3):268-9
pubmed: 25616063
Parasite Immunol. 2017 Mar;39(3):null
pubmed: 28112415
Adv Parasitol. 1968;6:63-116
pubmed: 4239747
Virchows Arch A Pathol Pathol Anat. 1971;354(2):136-49
pubmed: 5000755