Hair cortisol in the perinatal period mediates associations between maternal adversity and disrupted maternal interaction in early infancy.
disrupted maternal behavior
hair cortisol
maternal childhood abuse
perinatal period
severe mental illness
Journal
Developmental psychobiology
ISSN: 1098-2302
Titre abrégé: Dev Psychobiol
Pays: United States
ID NLM: 0164074
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
30
04
2018
revised:
13
12
2018
accepted:
17
12
2018
pubmed:
13
2
2019
medline:
25
1
2020
entrez:
13
2
2019
Statut:
ppublish
Résumé
Existing literature points to the possibility that cortisol could be one link between maternal adversity and poorer parenting quality, but most studies have examined salivary cortisol concentrations rather than hair cortisol concentrations. The current study examined hair cortisol concentration (HCC) during the third trimester of pregnancy as a mediator between maternal adversity indicators (childhood abuse, severe mental illness, symptomatic functioning) and maternal caregiving behavior at 4 months postpartum. Forty-four women participated in the study: 30 with severe mental disorders, and 14 nonclinical controls. HCC was assessed during the third trimester of pregnancy (HCC-P) and at 4 months postpartum (HCC-4M). Sexual, physical, and emotional abuse were assessed by the Adverse Childhood Experiences Study Questionnaire. Maternal disrupted interaction was reliably coded from mother-infant video interactions during a Still-Face Procedure. Mediation models indicated that maternal HCC-P and HCC-4M mediated associations between maternal psychopathology (severe mental illness, symptomatic functioning) and maternal disrupted interaction at 4 months. Maternal HCC at 4 months also mediated associations between experienced childhood abuse and overall disrupted interaction. Our findings indicate that HCC may be a potential early biomarker for future caregiving challenges among mothers with severe mental illness and histories of childhood abuse.
Identifiants
pubmed: 30747450
doi: 10.1002/dev.21833
pmc: PMC6545887
mid: NIHMS1029586
doi:
Substances chimiques
Hydrocortisone
WI4X0X7BPJ
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
543-556Subventions
Organisme : Chief Scientist Office
ID : CGA/19/13
Pays : United Kingdom
Organisme : NICHD NIH HHS
ID : R01 HD079484
Pays : United States
Informations de copyright
© 2019 Wiley Periodicals, Inc.
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