Regulation and role of endoglin in cholesterol-induced endothelial and vascular dysfunction
Animals
Aorta
/ cytology
Apolipoproteins E
/ genetics
Cells, Cultured
Cholesterol
/ metabolism
Endoglin
/ genetics
Endothelium, Vascular
/ drug effects
Female
Humans
Hypercholesterolemia
/ complications
Indazoles
/ pharmacology
Isonicotinic Acids
/ pharmacology
Kruppel-Like Factor 6
/ metabolism
Mice
Mice, Inbred C57BL
NF-kappa B
/ metabolism
Nitric Oxide
/ metabolism
Nitric Oxide Synthase Type III
/ metabolism
P-Selectin
/ metabolism
Plaque, Atherosclerotic
/ etiology
Receptors, LDL
/ genetics
Smad Proteins
/ metabolism
beta-Cyclodextrins
/ pharmacology
endothelial cells
hypercholesterolemia
mice
oxysterols
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
pubmed:
13
2
2019
medline:
19
5
2020
entrez:
13
2
2019
Statut:
ppublish
Résumé
Our objective was to investigate the effect of cholesterol [hypercholesterolemia and 7-ketocholesterol (7K)] on endoglin (Eng) expression and regulation with respect to endothelial or vascular dysfunction
Identifiants
pubmed: 30753095
doi: 10.1096/fj.201802245R
doi:
Substances chimiques
Apolipoproteins E
0
Endoglin
0
Indazoles
0
Isonicotinic Acids
0
Klf6 protein, mouse
0
Kruppel-Like Factor 6
0
NF-kappa B
0
P-Selectin
0
PHA 408
0
Receptors, LDL
0
Smad Proteins
0
beta-Cyclodextrins
0
Nitric Oxide
31C4KY9ESH
Cholesterol
97C5T2UQ7J
Nitric Oxide Synthase Type III
EC 1.14.13.39
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM