Laparoscopic Parenchymal-Sparing Hepatectomy: the New Maximally Minimal Invasive Surgery of the Liver-a Systematic Review and Meta-Analysis.


Journal

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
ISSN: 1873-4626
Titre abrégé: J Gastrointest Surg
Pays: United States
ID NLM: 9706084

Informations de publication

Date de publication:
04 2019
Historique:
received: 10 10 2018
accepted: 16 01 2019
pubmed: 14 2 2019
medline: 9 7 2020
entrez: 14 2 2019
Statut: ppublish

Résumé

Parenchymal-sparing hepatectomies (PSH) are liver resections with preservation of as much liver parenchyma as possible. PSH can be performed laparoscopically (LPSH), but access to the posterosuperior segments is difficult and they are challenging when there are multiple bilobar lesions; the procedure may require repositioning and may be long and cumbersome. The objective of this systematic review is to analyze the feasibility and limitations of laparoscopic PSH in the literature. A systematic review of the literature was performed by searching Medline/PubMed, Scopus, and Cochrane databases. Resections were categorized by segment(s), and data regarding operative time, blood loss, length of hospital stay, complications, and R0 resection were analyzed. Of 351 studies screened for relevance, 48 studies were reviewed. Ten publications fulfilled inclusion criteria, reporting data from 579 patients undergoing LPSH. The most common indication was CRLM (58%) followed by hepatocellular carcinoma (16%). Only 92 patients were reported to have resections of more than one tumor; the maximum number of lesions resected was seven. Of resected lesions, 21.5% were located in the cranial segments. Mean operating time was 335.2 min, estimated blood loss was 462 cc, and hospital stay was 7.6 days. Conversion rate was 9.7%, and complications occurred in 19.4% of cases. No perioperative mortality was reported. R0 resections were achieved in 87.7% of cases. Laparoscopic PSH is performed and reported, but the data quality is low so far. The main limitation of LPSH is the low number of lesions resected, especially for bilobar, metastatic disease. Prospective reports with tumor-specific oncological data are desirable.

Sections du résumé

BACKGROUND
Parenchymal-sparing hepatectomies (PSH) are liver resections with preservation of as much liver parenchyma as possible. PSH can be performed laparoscopically (LPSH), but access to the posterosuperior segments is difficult and they are challenging when there are multiple bilobar lesions; the procedure may require repositioning and may be long and cumbersome. The objective of this systematic review is to analyze the feasibility and limitations of laparoscopic PSH in the literature.
METHODS
A systematic review of the literature was performed by searching Medline/PubMed, Scopus, and Cochrane databases. Resections were categorized by segment(s), and data regarding operative time, blood loss, length of hospital stay, complications, and R0 resection were analyzed.
RESULTS
Of 351 studies screened for relevance, 48 studies were reviewed. Ten publications fulfilled inclusion criteria, reporting data from 579 patients undergoing LPSH. The most common indication was CRLM (58%) followed by hepatocellular carcinoma (16%). Only 92 patients were reported to have resections of more than one tumor; the maximum number of lesions resected was seven. Of resected lesions, 21.5% were located in the cranial segments. Mean operating time was 335.2 min, estimated blood loss was 462 cc, and hospital stay was 7.6 days. Conversion rate was 9.7%, and complications occurred in 19.4% of cases. No perioperative mortality was reported. R0 resections were achieved in 87.7% of cases.
CONCLUSION
Laparoscopic PSH is performed and reported, but the data quality is low so far. The main limitation of LPSH is the low number of lesions resected, especially for bilobar, metastatic disease. Prospective reports with tumor-specific oncological data are desirable.

Identifiants

pubmed: 30756316
doi: 10.1007/s11605-019-04128-w
pii: 10.1007/s11605-019-04128-w
doi:

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

860-869

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Auteurs

Jennifer A Kalil (JA)

Department of Surgery - Transplant Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Jelke Building 7th floor, Chicago, IL, 60612, USA.

Jennifer Poirier (J)

Department of Surgery - Transplant Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Jelke Building 7th floor, Chicago, IL, 60612, USA.

Bjoern Becker (B)

Department of Gastroenterology, Cantonal Hospital Winterthur, Brauerstr. 15, 8401, Winterthur, Switzerland.

Robert Van Dam (R)

Department of Surgery, Maastricht University Medical Center, P. Debyelaan 25, 6229 HX, Maastricht, The Netherlands.

Xavier Keutgen (X)

Department of Surgery - Transplant Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Jelke Building 7th floor, Chicago, IL, 60612, USA.

Erik Schadde (E)

Department of Surgery - Transplant Surgery, Rush University Medical Center, 1653 W. Congress Pkwy, Jelke Building 7th floor, Chicago, IL, 60612, USA. erik.schadde@uzh.ch.
Department of Surgery, Cantonal Hospital Winterthur, Brauerstr. 15, 8401, Winterthur, Switzerland. erik.schadde@uzh.ch.

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