Acute Effects of Hibiscus Sabdariffa Calyces on Postprandial Blood Pressure, Vascular Function, Blood Lipids, Biomarkers of Insulin Resistance and Inflammation in Humans.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
05 Feb 2019
Historique:
received: 30 11 2018
revised: 16 01 2019
accepted: 17 01 2019
entrez: 16 2 2019
pubmed: 16 2 2019
medline: 17 4 2019
Statut: epublish

Résumé

The acute impact of Hibiscus sabdariffa calyces (HSC) extract on postprandial vascular function and other cardiometabolic risk factors have not been studied previously. This study investigated the acute impact of HSC extract consumption on blood pressure (BP), vascular function and other cardiometabolic risk markers. Twenty-five men with 1% to 10% cardiovascular disease (CVD) risk (determined by QRISK Acute consumption of aqueous extract of HSC caused a significant increase in % FMD ( The extract of HSC improved postprandial vascular function and may be a useful dietary strategy to reduce endothelial dysfunction and CVD risk, although this requires confirmation.

Sections du résumé

BACKGROUND/OBJECTIVES OBJECTIVE
The acute impact of Hibiscus sabdariffa calyces (HSC) extract on postprandial vascular function and other cardiometabolic risk factors have not been studied previously. This study investigated the acute impact of HSC extract consumption on blood pressure (BP), vascular function and other cardiometabolic risk markers.
SUBJECTS/METHODS METHODS
Twenty-five men with 1% to 10% cardiovascular disease (CVD) risk (determined by QRISK
RESULTS RESULTS
Acute consumption of aqueous extract of HSC caused a significant increase in % FMD (
CONCLUSION CONCLUSIONS
The extract of HSC improved postprandial vascular function and may be a useful dietary strategy to reduce endothelial dysfunction and CVD risk, although this requires confirmation.

Identifiants

pubmed: 30764582
pii: nu11020341
doi: 10.3390/nu11020341
pmc: PMC6412462
pii:
doi:

Substances chimiques

Biomarkers 0
Lipids 0
Plant Extracts 0

Types de publication

Journal Article Randomized Controlled Trial

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Tertiary Education Trust Fund
ID : None

Déclaration de conflit d'intérêts

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

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Auteurs

Salisu M Abubakar (SM)

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, Reading, RG6 6AP, UK. smabubakar.bch@buk.edu.ng.
Department of Biochemistry, Bayero University, P.M.B. 3011, Kano, Nigeria. smabubakar.bch@buk.edu.ng.

Moses T Ukeyima (MT)

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, Reading, RG6 6AP, UK. mosesukeyima@gmail.com.
Department of Food Science and Technology, University of Agriculture, P.M.B. 2373, Makurdi, Nigeria. mosesukeyima@gmail.com.

Jeremy P E Spencer (JPE)

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, Reading, RG6 6AP, UK. j.p.e.spencer@reading.ac.uk.
Molecular Nutrition Group, Centre for Integrative Neuroscience and Neurodynamics, University of Reading, RG6 6AP, Reading, UK. j.p.e.spencer@reading.ac.uk.

Julie A Lovegrove (JA)

Hugh Sinclair Unit of Human Nutrition, Department of Food and Nutritional Sciences and Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, Reading, RG6 6AP, UK. j.a.lovegrove@reading.ac.uk.

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