Responsiveness and minimal clinically important difference of the Minnesota living with heart failure questionnaire.
Health-related quality of life
Heart failure
Minimal clinically important difference
Minnesota living with heart failure questionnaire
Psychometric properties
Responsiveness
Journal
Health and quality of life outcomes
ISSN: 1477-7525
Titre abrégé: Health Qual Life Outcomes
Pays: England
ID NLM: 101153626
Informations de publication
Date de publication:
14 Feb 2019
14 Feb 2019
Historique:
received:
06
09
2018
accepted:
07
02
2019
entrez:
16
2
2019
pubmed:
16
2
2019
medline:
21
3
2019
Statut:
epublish
Résumé
The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is one of the most widely used health-related quality of life questionnaires for patients with heart failure (HF). The objective of the present study was to explore the responsiveness of the MLHFQ by estimating the minimal detectable change (MDC) and the minimal clinically important difference (MCID) in Spain. Patients hospitalized for HF in the participating hospitals completed the MLHFQ at baseline and 6 months, plus anchor questions at 6 months. To study responsiveness, patients were classified as having "improved", remained "the same" or "worsened", using anchor questions. We used the standardized effect size (SES), and standardized response mean (SRM) to measure the magnitude of the changes scores and calculate the MDC and MCID. Overall, 1211 patients completed the baseline and follow-up questionnaires 6 months after discharge. The mean changes in all MLHFQ domains followed a trend (P < 0.0001) with larger gains in quality of life among patients classified as "improved", smaller gains among those classified as "the same", and losses among those classified as "worsened". The SES and SRM responsiveness parameters in the "improved" group were ≥ 0.80 on nearly all scales. Among patients classified as "worsened", effect sizes were < 0.40, while among patients classified as "the same", the values ranged from 0.24 to 0.52. The MDC ranged from 7.27 to 16.96. The MCID based on patients whose response to the anchor question was "somewhat better", ranged from 3.59 to 19.14 points. All of these results suggest that all domains of the MLHFQ have a good sensitivity to change in the population studied.
Sections du résumé
BACKGROUND
BACKGROUND
The Minnesota Living with Heart Failure Questionnaire (MLHFQ) is one of the most widely used health-related quality of life questionnaires for patients with heart failure (HF). The objective of the present study was to explore the responsiveness of the MLHFQ by estimating the minimal detectable change (MDC) and the minimal clinically important difference (MCID) in Spain.
METHODS
METHODS
Patients hospitalized for HF in the participating hospitals completed the MLHFQ at baseline and 6 months, plus anchor questions at 6 months. To study responsiveness, patients were classified as having "improved", remained "the same" or "worsened", using anchor questions. We used the standardized effect size (SES), and standardized response mean (SRM) to measure the magnitude of the changes scores and calculate the MDC and MCID.
RESULTS
RESULTS
Overall, 1211 patients completed the baseline and follow-up questionnaires 6 months after discharge. The mean changes in all MLHFQ domains followed a trend (P < 0.0001) with larger gains in quality of life among patients classified as "improved", smaller gains among those classified as "the same", and losses among those classified as "worsened". The SES and SRM responsiveness parameters in the "improved" group were ≥ 0.80 on nearly all scales. Among patients classified as "worsened", effect sizes were < 0.40, while among patients classified as "the same", the values ranged from 0.24 to 0.52. The MDC ranged from 7.27 to 16.96. The MCID based on patients whose response to the anchor question was "somewhat better", ranged from 3.59 to 19.14 points.
CONCLUSIONS
CONCLUSIONS
All of these results suggest that all domains of the MLHFQ have a good sensitivity to change in the population studied.
Identifiants
pubmed: 30764842
doi: 10.1186/s12955-019-1104-2
pii: 10.1186/s12955-019-1104-2
pmc: PMC6376687
doi:
Types de publication
Journal Article
Validation Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
36Subventions
Organisme : Instituto de Salud Carlos III
ID : PS09/01129
Organisme : Instituto de Salud Carlos III
ID : PS09/00865
Organisme : Instituto de Salud Carlos III
ID : PS09/01053
Organisme : Instituto de Salud Carlos III
ID : PS09/01770
Organisme : Department of Health of Basque Government
ID : 2008111017
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