Fate mapping reveals the age structure of the peripheral T cell compartment.
CD8+ T cells
T cell homeostasis
immunology
mathematical modeling
ontogeny
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
05 03 2019
05 03 2019
Historique:
pubmed:
16
2
2019
medline:
18
3
2020
entrez:
16
2
2019
Statut:
ppublish
Résumé
Accumulating evidence indicates that the immune system does not develop in a linear fashion, but rather as distinct developmental layers formed from sequential waves of hematopoietic stem cells, each giving rise to unique populations of immune cells at different stages of development. Although recent studies have indicated that conventional CD8
Identifiants
pubmed: 30765525
pii: 1811634116
doi: 10.1073/pnas.1811634116
pmc: PMC6410819
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3974-3981Subventions
Organisme : NIAID NIH HHS
ID : R01 AI105265
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI110613
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB023860
Pays : United States
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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