[Sublobar Resection for Patients with a Metachronous Second Primary Lung Cancer Following Curative Resection of a Primary Lung Cancer].
Journal
Kyobu geka. The Japanese journal of thoracic surgery
ISSN: 0021-5252
Titre abrégé: Kyobu Geka
Pays: Japan
ID NLM: 0413533
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
entrez:
16
2
2019
pubmed:
16
2
2019
medline:
4
4
2019
Statut:
ppublish
Résumé
Surgical methods for patients with a metachronous 2nd primary lung cancer following curative resection of a primary lung cancer remain controversial. The purpose of this study was to evaluate the outcomes of patients who underwent sublobar resection for a metachronous 2nd primary lung cancer. We retrospectively analyzed 10 patients who underwent sublobar resection for a metachronous 2nd primary lung cancer occurring 5 years or more after the initial surgery for primary lung cancer. The 5-year overall survival rate after the 2nd surgery was 68.6%. There was no operative mortality. A postoperative recurrence developed in 4 patients, 3 of whom had pathological stage ⅠA3 cancer. Moreover, patients with a stage ⅠA3 metachronous 2nd primary lung cancer had significantly lower 5-year disease-free and overall survival rates than patients with a stage ⅠA1 or ⅠA2 cancer( disease-free survival rate, p=0.022;overall survival rate, p=0.023). For patients with a stage ⅠA1 or ⅠA2 metachronous 2nd primary lung cancer, sublobar resection may be acceptable because those patients had a good prognosis in this study. Early detection of a metachronous 2nd primary lung cancer following the initial surgery may be very important for improving the patient's prognosis.
Sections du résumé
BACKGROUND
BACKGROUND
Surgical methods for patients with a metachronous 2nd primary lung cancer following curative resection of a primary lung cancer remain controversial. The purpose of this study was to evaluate the outcomes of patients who underwent sublobar resection for a metachronous 2nd primary lung cancer.
METHODS
METHODS
We retrospectively analyzed 10 patients who underwent sublobar resection for a metachronous 2nd primary lung cancer occurring 5 years or more after the initial surgery for primary lung cancer.
RESULTS
RESULTS
The 5-year overall survival rate after the 2nd surgery was 68.6%. There was no operative mortality. A postoperative recurrence developed in 4 patients, 3 of whom had pathological stage ⅠA3 cancer. Moreover, patients with a stage ⅠA3 metachronous 2nd primary lung cancer had significantly lower 5-year disease-free and overall survival rates than patients with a stage ⅠA1 or ⅠA2 cancer( disease-free survival rate, p=0.022;overall survival rate, p=0.023).
CONCLUSIONS
CONCLUSIONS
For patients with a stage ⅠA1 or ⅠA2 metachronous 2nd primary lung cancer, sublobar resection may be acceptable because those patients had a good prognosis in this study. Early detection of a metachronous 2nd primary lung cancer following the initial surgery may be very important for improving the patient's prognosis.
Types de publication
Journal Article
Langues
jpn
Sous-ensembles de citation
IM