Cannabinoid CB


Journal

British journal of pharmacology
ISSN: 1476-5381
Titre abrégé: Br J Pharmacol
Pays: England
ID NLM: 7502536

Informations de publication

Date de publication:
05 2019
Historique:
received: 29 08 2018
revised: 11 12 2018
accepted: 30 01 2019
pubmed: 16 2 2019
medline: 16 7 2020
entrez: 16 2 2019
Statut: ppublish

Résumé

Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB In the present study, we used the electrical intracranial self-stimulation paradigm to evaluate the effects of various cannabinoid drugs on brain reward in laboratory rats and the roles of CB Two mixed CB CB

Sections du résumé

BACKGROUND AND PURPOSE
Endocannabinoids are critically involved in brain reward functions, mediated by activation of CB
EXPERIMENTAL APPROACH
In the present study, we used the electrical intracranial self-stimulation paradigm to evaluate the effects of various cannabinoid drugs on brain reward in laboratory rats and the roles of CB
KEY RESULTS
Two mixed CB
CONCLUSIONS AND IMPLICATIONS
CB

Identifiants

pubmed: 30767215
doi: 10.1111/bph.14625
pmc: PMC6468271
doi:

Substances chimiques

Cannabinoids 0
Receptor, Cannabinoid, CB1 0
Receptor, Cannabinoid, CB2 0

Types de publication

Journal Article Research Support, N.I.H., Intramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1268-1281

Informations de copyright

© 2019 The British Pharmacological Society.

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Auteurs

Krista J Spiller (KJ)

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Guo-Hua Bi (GH)

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.

Yi He (Y)

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.

Ewa Galaj (E)

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.

Eliot L Gardner (EL)

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.

Zheng-Xiong Xi (ZX)

Molecular Targets and Medications Discovery Branch, Intramural Research Program, National Institute on Drug Abuse, Baltimore, Maryland, USA.

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Classifications MeSH