Prescription Drug Misuse: Sources of Controlled Medications in Adolescents.
Adolescent
Analgesics, Opioid
Central Nervous System Stimulants
Child
Depressive Disorder, Major
/ epidemiology
Female
Health Surveys
Humans
Hypnotics and Sedatives
Logistic Models
Male
Prescription Drug Misuse
/ statistics & numerical data
Prescription Drugs
/ classification
Student Dropouts
/ statistics & numerical data
Substance-Related Disorders
/ epidemiology
Tranquilizing Agents
United States
/ epidemiology
opioid
source
stimulant
tranquilizer
Journal
Journal of the American Academy of Child and Adolescent Psychiatry
ISSN: 1527-5418
Titre abrégé: J Am Acad Child Adolesc Psychiatry
Pays: United States
ID NLM: 8704565
Informations de publication
Date de publication:
07 2019
07 2019
Historique:
received:
12
06
2018
revised:
12
09
2018
accepted:
24
10
2018
pubmed:
16
2
2019
medline:
20
8
2020
entrez:
16
2
2019
Statut:
ppublish
Résumé
Adolescent controlled prescription drug misuse (PDM) co-occurs with significant consequences, including lower educational achievement, substance use disorder (SUD) symptoms, and psychopathology. Nonetheless, adolescent PDM sources and the prevalence of other substance use, SUD, and mental health outcomes associated with sources remain poorly understood. Data were from the 2009 to 2014 National Survey on Drug Use and Health, including 103,920 adolescents (12-17 years of age). Six mutually exclusive sources were used: physician source only, theft/fake prescription only, friend/relative for free only, purchases only, other source only, or multiple sources. Analyses occurred separately for prescription opioids, stimulants, and tranquilizer/sedatives. PDM source prevalence across adolescents and by sex and school enrollment/engagement were estimated. Adjusted odds of past-year DSM-IV substance-specific SUD, marijuana use, any SUD, major depressive disorder (MDD), anxiety diagnosis, mental health treatment, and past-month binge drinking were estimated by source. Friends/relatives, for free, was the most common source (29.0%-33.2%), followed by physician sources for opioids (23.9%), purchases for stimulants (23.5%), and tranquilizer/sedatives (22.7%). Few school enrollment/engagement differences existed, but female adolescents were more likely to use multiple sources. Over 70% of adolescents using multiple sources had a past-year SUD. Multiple sources, purchases, and theft/fake prescription were more strongly associated with other substance use than physician source use, and multiple source use was linked with MDD. Adolescents using multiple sources, purchases and theft/fake prescriptions have elevated rates of other substance use, SUD and MDD and particularly warrant intervention. Also, adolescents with other SUD and MDD should be screened for PDM and misuse sources.
Identifiants
pubmed: 30768405
pii: S0890-8567(18)31912-9
doi: 10.1016/j.jaac.2018.09.438
pmc: PMC6491250
mid: NIHMS1511120
pii:
doi:
Substances chimiques
Analgesics, Opioid
0
Central Nervous System Stimulants
0
Hypnotics and Sedatives
0
Prescription Drugs
0
Tranquilizing Agents
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
670-680.e4Subventions
Organisme : NIDA NIH HHS
ID : R01 DA031160
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA043691
Pays : United States
Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright © 2018 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.
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