Antibiotics for Groin Hernia Repair According to Evidence-Based Guidelines: Time for Action in Ghana.


Journal

The Journal of surgical research
ISSN: 1095-8673
Titre abrégé: J Surg Res
Pays: United States
ID NLM: 0376340

Informations de publication

Date de publication:
06 2019
Historique:
received: 07 10 2018
revised: 05 11 2018
accepted: 11 01 2019
pubmed: 16 2 2019
medline: 15 2 2020
entrez: 16 2 2019
Statut: ppublish

Résumé

Groin hernia repairs (GHR), though classified as clean surgeries, are associated with varying rates of surgical site infections. We assessed the practices of surgeons in Ghana regarding antibiotic use for GHR in comparison to evidence-based international guidelines (EBIG). We interviewed surgeons trained by the Ghana College of Physicians and Surgeons (GCPS), from inception (2003) through 2016, about their use of antibiotics for GHR. We defined the outcome variable of consistently following EBIG in antibiotics use for GHR. Logistic regression was used to examine how a priori selected covariates contributed to the outcome. Eighty-two of 117 surgeons reported performing/supervising at least one GHR per week. They performed/supervised a mean of five GHR per week. Thirty-two (40%) reported using mesh for at least 50% of GHR. For primary GHR, 75% of surgeons administered antibiotics according to EBIG, whereas for GHR with mesh only, 45% did so. Predictors of consistently following EBIG were increasing number of GHR performed per week (adjusted odds ratio 1.44, 95% CI 1.07-1.96) and increasing time spent for clinical work (adjusted odds ratio 0.95, 95% CI 0.91-0.99). Years of practice since GCPS graduation, total operations performed per week, and hospital level of practice were not predictive of the outcome variable. Two-thirds of Ghanaian surgeons interviewed do not consistently administer antibiotics for GHR per EBIG, raising the need to improve access to evidence-based medical information overall to guide practice. Determining local surgical site infections rates to guide antibiotic use in GHR will be useful in Ghana and other LMICs.

Identifiants

pubmed: 30769249
pii: S0022-4804(19)30047-2
doi: 10.1016/j.jss.2019.01.040
pmc: PMC6451880
mid: NIHMS1519231
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

90-95

Subventions

Organisme : FIC NIH HHS
ID : D43 TW007267
Pays : United States

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

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Auteurs

Adam Gyedu (A)

Department of Surgery, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana; University Hospital, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana. Electronic address: drgyedu@gmail.com.

Micah Katz (M)

Department of Surgery, University of Utah, Salt Lake City, Utah.

Kwabena Agbedinu (K)

Directorate of Surgery, Komfo Anokye Teaching Hospital, Kumasi, Ghana.

Peter Donkor (P)

Department of Surgery, School of Medical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Charles Mock (C)

Harborview Injury Prevention & Research Center, Seattle, Washington; Department of Surgery, University of Washington, Seattle, Washington.

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