The Dexcom glucose monitoring system-An isobornyl acrylate-free alternative for diabetic patients.
Dexcom
Freestyle Libre
acrylates
allergic contact dermatitis
continuous glucose monitoring systems
flash glucose monitoring system
insulin pump
isobornyl acrylate
patch test
Journal
Contact dermatitis
ISSN: 1600-0536
Titre abrégé: Contact Dermatitis
Pays: England
ID NLM: 7604950
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
31
12
2018
revised:
13
02
2019
accepted:
17
02
2019
pubmed:
21
2
2019
medline:
24
12
2019
entrez:
21
2
2019
Statut:
ppublish
Résumé
Glucose monitoring systems, for example, Freestyle Libre (Abott) and Dexcom (Nintamed), are increasingly being used instead of conventional blood sugar measurement. However, many patients have experienced adverse skin reactions such as severe allergic contact dermatitis (ACD). Finally, in August 2017, the culprit allergen in Freestyle Libre, isobornyl acrylate (IBOA), was identified. After patients have developed ACD, it is recommended that they no longer use their glucose monitoring systems. Thus, it is important to find an alternative IBOA-free device. Five patients presented with ACD caused by Freestyle Libre. Each was patch tested with allergens from the baseline series and from a plastics and glues series, and additionally with IBOA 0.1% pet. Gas chromatography-mass spectrometry (GC/MS) of the Freestyle Libre sensor and the Dexcom sensor was performed. The Dexcom sensor remained on the skin of all patients for at least 2 days. All patients were sensitized to IBOA. GC/MS showed the presence of IBOA in the Freestyle Libre sensor, whereas the Dexcom sensor was IBOA-free. None of the patients had skin reactions to the Dexcom sensor. Patients with Freestyle Libre and IBOA allergy may use the Dexcom sensor as an alternative for glucose monitoring.
Sections du résumé
BACKGROUND
BACKGROUND
Glucose monitoring systems, for example, Freestyle Libre (Abott) and Dexcom (Nintamed), are increasingly being used instead of conventional blood sugar measurement. However, many patients have experienced adverse skin reactions such as severe allergic contact dermatitis (ACD). Finally, in August 2017, the culprit allergen in Freestyle Libre, isobornyl acrylate (IBOA), was identified.
OBJECTIVES
OBJECTIVE
After patients have developed ACD, it is recommended that they no longer use their glucose monitoring systems. Thus, it is important to find an alternative IBOA-free device.
PATIENTS AND METHODS
METHODS
Five patients presented with ACD caused by Freestyle Libre. Each was patch tested with allergens from the baseline series and from a plastics and glues series, and additionally with IBOA 0.1% pet. Gas chromatography-mass spectrometry (GC/MS) of the Freestyle Libre sensor and the Dexcom sensor was performed. The Dexcom sensor remained on the skin of all patients for at least 2 days.
RESULTS
RESULTS
All patients were sensitized to IBOA. GC/MS showed the presence of IBOA in the Freestyle Libre sensor, whereas the Dexcom sensor was IBOA-free. None of the patients had skin reactions to the Dexcom sensor.
CONCLUSIONS
CONCLUSIONS
Patients with Freestyle Libre and IBOA allergy may use the Dexcom sensor as an alternative for glucose monitoring.
Substances chimiques
Acrylates
0
Adhesives
0
Camphanes
0
isobornyl acrylate
IX0PRH184P
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
32-36Informations de copyright
© 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.