High-resolution data-driven model of the mouse connectome.
Connectome
Mouse
Whole-brain
Journal
Network neuroscience (Cambridge, Mass.)
ISSN: 2472-1751
Titre abrégé: Netw Neurosci
Pays: United States
ID NLM: 101719149
Informations de publication
Date de publication:
2019
2019
Historique:
received:
04
04
2018
accepted:
31
07
2018
entrez:
23
2
2019
pubmed:
23
2
2019
medline:
23
2
2019
Statut:
epublish
Résumé
Knowledge of mesoscopic brain connectivity is important for understanding inter- and intraregion information processing. Models of structural connectivity are typically constructed and analyzed with the assumption that regions are homogeneous. We instead use the Allen Mouse Brain Connectivity Atlas to construct a model of whole-brain connectivity at the scale of 100 μm voxels. The data consist of 428 anterograde tracing experiments in wild type C57BL/6J mice, mapping fluorescently labeled neuronal projections brain-wide. Inferring spatial connectivity with this dataset is underdetermined, since the approximately 2 × 10
Identifiants
pubmed: 30793081
doi: 10.1162/netn_a_00066
pii: netn_a_00066
pmc: PMC6372022
doi:
Types de publication
Journal Article
Langues
eng
Pagination
217-236Subventions
Organisme : NIA NIH HHS
ID : R01 AG047589
Pays : United States
Organisme : NCI NIH HHS
ID : T32 CA206089
Pays : United States
Organisme : NIMH NIH HHS
ID : U01 MH105982
Pays : United States
Organisme : NIMH NIH HHS
ID : U19 MH114830
Pays : United States
Déclaration de conflit d'intérêts
Competing Interests: The authors have declared that no competing interests exist.
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