Grisel Syndrome in Pediatric Age: A Single-Center Italian Experience and Review of the Literature.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
05 2019
Historique:
received: 14 11 2018
revised: 05 02 2019
accepted: 06 02 2019
pubmed: 25 2 2019
medline: 19 11 2019
entrez: 25 2 2019
Statut: ppublish

Résumé

Nontraumatic atlantoaxial subluxation, also known as Grisel syndrome, is a rare disease that usually affects children. The typical presentation is torticollis in patients with a history of surgical operations or airway infections. We describe 5 patients with Grisel syndrome, referring to medical care for a torticollis, a few weeks after an airway infection, with no trauma associated. Radiologic confirmation of the diagnosis, with computed tomography and magnetic resonance imaging studies, was carried out. The patients were treated with external immobilization for 3 months, followed by surgical fixation in the case of recurrence after collar removal or inveterate subluxation. We performed a review of the literature to define the best management of this disease. Management of Grisel syndrome depends on the degree of subluxation basing on the Fielding and Hawkins classification. The initial nonsurgical management consists of close reduction and immobilization. Surgical fixation is indicated in cases of conservative treatment failure.

Sections du résumé

BACKGROUND
Nontraumatic atlantoaxial subluxation, also known as Grisel syndrome, is a rare disease that usually affects children. The typical presentation is torticollis in patients with a history of surgical operations or airway infections.
METHODS
We describe 5 patients with Grisel syndrome, referring to medical care for a torticollis, a few weeks after an airway infection, with no trauma associated. Radiologic confirmation of the diagnosis, with computed tomography and magnetic resonance imaging studies, was carried out.
RESULTS
The patients were treated with external immobilization for 3 months, followed by surgical fixation in the case of recurrence after collar removal or inveterate subluxation. We performed a review of the literature to define the best management of this disease.
CONCLUSIONS
Management of Grisel syndrome depends on the degree of subluxation basing on the Fielding and Hawkins classification. The initial nonsurgical management consists of close reduction and immobilization. Surgical fixation is indicated in cases of conservative treatment failure.

Identifiants

pubmed: 30797917
pii: S1878-8750(19)30446-2
doi: 10.1016/j.wneu.2019.02.035
pii:
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

374-382

Informations de copyright

Copyright © 2019 Elsevier Inc. All rights reserved.

Auteurs

Pasquale Anania (P)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy; Neurosurgery, Department of Neurosciences (DINOGMI), Policlinico San Martino, University of Genoa, Genoa, Italy. Electronic address: pas.anania@gmail.com.

Piero Pavone (P)

Department of Pediatrics, University Hospital B Policlinico-Vittorio Emanuele, Catania, Italy; Department of Pediatrics, AOU Policlinico-Vittorio Emanuele, University of Catania, Catania, Italy.

Mattia Pacetti (M)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

Monica Truffelli (M)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy; Neurosurgery, Department of Neurosciences (DINOGMI), Policlinico San Martino, University of Genoa, Genoa, Italy.

Marco Pavanello (M)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

Marcello Ravegnani (M)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

Alessandro Consales (A)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

Armando Cama (A)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

Gianluca Piatelli (G)

Neurosurgery, Pediatric Hospital Giannina Gaslini, University of Genoa, Genoa, Italy.

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