Speech intelligibility in patients with oral cancer: An objective baseline evaluation of pretreatment function and impairment.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
04 2019
Historique:
received: 25 02 2018
revised: 07 08 2018
accepted: 06 10 2018
pubmed: 26 2 2019
medline: 10 10 2020
entrez: 26 2 2019
Statut: ppublish

Résumé

This study seeks to identify those factors that influence the pre-therapeutic speech intelligibility in patients with oral squamous cell carcinoma (OSCC). A group of 172 patients (125 males, 47 females, mean age = 61 ± 11 a) with different OSCC stages ranging from T1 to T4 and N0 to N2 was examined for their speech intelligibility using a computerized measuring tool, and compared to a healthy reference group (30 males, 10 females, mean age = 59 ± 12 a). It was found that the pre-therapeutic speech intelligibility in patients with OSCC is decreased when compared to a healthy collective. Two demographic factors that influence speech intelligibility could be identified: sex and age. It was determined that the only disease-related factor that influences speech intelligibility before therapy is the location of the tumor. The results of this study reveal that a preoperative speech intelligibility impairment in patients suffering from OSCC occurs independent of tumor stage, size of the tumor and infiltration status.

Sections du résumé

BACKGROUND
This study seeks to identify those factors that influence the pre-therapeutic speech intelligibility in patients with oral squamous cell carcinoma (OSCC).
METHOD
A group of 172 patients (125 males, 47 females, mean age = 61 ± 11 a) with different OSCC stages ranging from T1 to T4 and N0 to N2 was examined for their speech intelligibility using a computerized measuring tool, and compared to a healthy reference group (30 males, 10 females, mean age = 59 ± 12 a).
RESULTS
It was found that the pre-therapeutic speech intelligibility in patients with OSCC is decreased when compared to a healthy collective. Two demographic factors that influence speech intelligibility could be identified: sex and age. It was determined that the only disease-related factor that influences speech intelligibility before therapy is the location of the tumor.
CONCLUSION
The results of this study reveal that a preoperative speech intelligibility impairment in patients suffering from OSCC occurs independent of tumor stage, size of the tumor and infiltration status.

Identifiants

pubmed: 30801814
doi: 10.1002/hed.25527
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1063-1069

Informations de copyright

© 2019 Wiley Periodicals, Inc.

Auteurs

Florian Stelzle (F)

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany.

Nicolai Oetter (N)

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany.

Luisa Theresa Goellner (LT)

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany.

Werner Adler (W)

Department of Medical Informatics, Biometry and Epidemiology (IMBE), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.

Maximilian Rohde (M)

Department of Oral and Maxillofacial Surgery, Ludwig-Maximilian-University Munich, University Hospital Munich, Munich, Germany.

Andreas Maier (A)

Department of Computer Science 5, Friedrich-Alexander University Erlangen-Nürnberg, Erlangen, Germany.

Levi Matthies (L)

Department of Oral and Maxillofacial Surgery, University of Hamburg (UHH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Marco Rainer Kesting (MR)

Department of Oral and Maxillofacial Surgery, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), University Hospital Erlangen, Erlangen, Germany.

Christian Knipfer (C)

Department of Oral and Maxillofacial Surgery, University of Hamburg (UHH), University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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Classifications MeSH