Comparison of endothelial promoter efficiency and specificity in mice reveals a subset of Pdgfb-positive hematopoietic cells.
Alleles
Animals
Brain
/ metabolism
Endothelial Cells
/ cytology
Hematopoietic Stem Cells
/ cytology
Hemostasis
Integrases
/ metabolism
Kidney
/ metabolism
Liver
/ metabolism
Lung
/ metabolism
Lymphokines
/ genetics
Mice
Mice, Transgenic
Myocardium
/ metabolism
Platelet-Derived Growth Factor
/ genetics
Polymerase Chain Reaction
Retina
/ metabolism
Tamoxifen
/ pharmacology
Thrombosis
/ metabolism
Cre recombinase
blood vessels
endothelial cells
hematopoietic system
tamoxifen
transgenic mice
Journal
Journal of thrombosis and haemostasis : JTH
ISSN: 1538-7836
Titre abrégé: J Thromb Haemost
Pays: England
ID NLM: 101170508
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
08
01
2019
pubmed:
26
2
2019
medline:
11
7
2020
entrez:
26
2
2019
Statut:
ppublish
Résumé
Essentials To reliably study the respective roles of blood and endothelial cells in hemostasis, mouse models with a strong and specific endothelial expression of the Cre recombinase are needed. Using mT/mG reporter mice and conditional JAK2
Identifiants
pubmed: 30801958
doi: 10.1111/jth.14417
pii: S1538-7836(22)05357-0
doi:
Substances chimiques
Lymphokines
0
Pdgfd protein, mouse
0
Platelet-Derived Growth Factor
0
Tamoxifen
094ZI81Y45
Cre recombinase
EC 2.7.7.-
Integrases
EC 2.7.7.-
Types de publication
Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
827-840Informations de copyright
© 2019 International Society on Thrombosis and Haemostasis.