Management of acute radiation dermatitis: A review of the literature and proposal for treatment algorithm.

aloe vera ascorbic acid calendula catechins chamomile corticosteroids dermatitis epidermal growth factor granulocyte macrophage-colony stimulating factor hyaluronic acid management pantothenic acid prevention radiation radiation dermatitis radiation oncology radiation-induced skin toxicity radiotherapy silver clear nylon dressing silver sulfadiazine statins steroids sucralfate topical topical agents treatment trolamine washing β-sitosterol

Journal

Journal of the American Academy of Dermatology
ISSN: 1097-6787
Titre abrégé: J Am Acad Dermatol
Pays: United States
ID NLM: 7907132

Informations de publication

Date de publication:
Aug 2019
Historique:
received: 20 12 2018
revised: 17 02 2019
accepted: 20 02 2019
pubmed: 26 2 2019
medline: 21 12 2019
entrez: 26 2 2019
Statut: ppublish

Résumé

Radiation dermatitis is a common sequela of radiation therapy; up to 95% of patients will develop moderate-to-severe skin reactions. No criterion standard currently exists for the treatment of acute radiation-induced skin toxicity. It is therefore imperative to develop a greater understanding of management options available to allow clinicians to make informed decisions when managing radiation oncology patients. This literature review discusses the topical agents that have been studied for the treatment of acute radiation dermatitis, reviews their mechanisms of action, and presents a treatment algorithm for clinicians managing patients experiencing radiation dermatitis.

Identifiants

pubmed: 30802561
pii: S0190-9622(19)30338-X
doi: 10.1016/j.jaad.2019.02.047
pii:
doi:

Substances chimiques

Adrenal Cortex Hormones 0
Anti-Infective Agents, Local 0
Biological Products 0
Dermatologic Agents 0
Ethanolamines 0
Hydroxymethylglutaryl-CoA Reductase Inhibitors 0
Plant Preparations 0
Vitamins 0
Sucralfate 54182-58-0
triethanolamine 9O3K93S3TK
Silver Sulfadiazine W46JY43EJR

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

558-567

Informations de copyright

Copyright © 2019 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

Auteurs

Amanda Rosenthal (A)

University of Miami Miller School of Medicine, Miami, Florida; Moy-Fincher-Chipps Facial Plastics & Dermatology, Beverly Hills, California. Electronic address: ahr52@med.miami.edu.

Rachel Israilevich (R)

Moy-Fincher-Chipps Facial Plastics & Dermatology, Beverly Hills, California.

Ronald Moy (R)

Moy-Fincher-Chipps Facial Plastics & Dermatology, Beverly Hills, California.

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Classifications MeSH