A Dopaminergic Basis for Fear Extinction.
consolidation
fear conditioning
memory
prediction error
reinforcement learning
reward
Journal
Trends in cognitive sciences
ISSN: 1879-307X
Titre abrégé: Trends Cogn Sci
Pays: England
ID NLM: 9708669
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
17
12
2018
revised:
28
01
2019
accepted:
28
01
2019
pubmed:
26
2
2019
medline:
18
9
2020
entrez:
27
2
2019
Statut:
ppublish
Résumé
It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.
Identifiants
pubmed: 30803871
pii: S1364-6613(19)30041-5
doi: 10.1016/j.tics.2019.01.013
pii:
doi:
Substances chimiques
Dopamine
VTD58H1Z2X
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
274-277Informations de copyright
Copyright © 2019 Elsevier Ltd. All rights reserved.