A Dopaminergic Basis for Fear Extinction.


Journal

Trends in cognitive sciences
ISSN: 1879-307X
Titre abrégé: Trends Cogn Sci
Pays: England
ID NLM: 9708669

Informations de publication

Date de publication:
04 2019
Historique:
received: 17 12 2018
revised: 28 01 2019
accepted: 28 01 2019
pubmed: 26 2 2019
medline: 18 9 2020
entrez: 27 2 2019
Statut: ppublish

Résumé

It is a joyous relief when an event we dread fails to materialize. In fear extinction, the appetitive nature of an omitted aversive event is not a mere epiphenomenon but drives the reduction of fear responses and the formation of long-term extinction memories. Dopamine emerges as key neurobiological mediator of these related processes.

Identifiants

pubmed: 30803871
pii: S1364-6613(19)30041-5
doi: 10.1016/j.tics.2019.01.013
pii:
doi:

Substances chimiques

Dopamine VTD58H1Z2X

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

274-277

Informations de copyright

Copyright © 2019 Elsevier Ltd. All rights reserved.

Auteurs

Raffael Kalisch (R)

Deutsches Resilienz Zentrum (DRZ), Johannes Gutenberg University Medical Center, Mainz, Germany; Neuroimaging Center (NIC), Focus Program Translational Neuroscience (FTN), Johannes Gutenberg University Medical Center, Mainz, Germany. Electronic address: rkalisch@uni-mainz.de.

Anna M V Gerlicher (AMV)

Department of Clinical Psychology, University of Amsterdam, Amsterdam, The Netherlands.

Sevil Duvarci (S)

Institute of Neurophysiology, Neuroscience Center, Goethe University, Frankfurt, Germany.

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Classifications MeSH