Kimura disease: a case report of a rare illness presenting as a common complaint.
Abscess
/ pathology
Angiolymphoid Hyperplasia with Eosinophilia
/ diagnosis
Anti-Bacterial Agents
/ therapeutic use
Biopsy
Child
Delayed Diagnosis
/ adverse effects
Diagnosis, Differential
Drainage
Fever
/ diagnosis
Head and Neck Neoplasms
/ pathology
Humans
Immunologic Factors
/ administration & dosage
Lymphadenitis
/ diagnosis
Lymphadenopathy
/ etiology
Male
Parotitis
/ diagnosis
Steroids
/ administration & dosage
Kimura disease
anchoring bias
care fragmentation
cervical lymphadenopathy
parotiditis
pediatric
Journal
Diagnosis (Berlin, Germany)
ISSN: 2194-802X
Titre abrégé: Diagnosis (Berl)
Pays: Germany
ID NLM: 101654734
Informations de publication
Date de publication:
26 11 2019
26 11 2019
Historique:
received:
24
10
2018
accepted:
28
01
2019
pubmed:
28
2
2019
medline:
9
4
2020
entrez:
28
2
2019
Statut:
ppublish
Résumé
Background Kimura is an uncommon inflammatory cause of pediatric head and neck masses due to eosinophilic infiltration of unclear etiology. Kimura can present similarly to infectious lymphadenitis, a much more common pediatric complaint. This case explores the role of anchoring bias when faced with an illness that at first appears to fit a common illness script that led to a delayed diagnosis. Case presentation A 7-year-old boy presented with acute onset of pre-auricular lymphadenopathy and fevers initially thought to be most consistent with infectious cervical lymphadenopathy. Despite treatment with broad spectrum antibiotics and multiple evaluations for underlying abscess requiring surgical drainage, the patient did not improve and remained febrile. Eventually, excisional lymph node biopsy was obtained and a pathologic diagnosis of Kimura disease was made. Conclusions This case illustrates an uncommon pediatric diagnosis which presented similarly to infectious cervical lymphadenitis without additional laboratory features consistent with Kimura. We highlight the role of anchoring bias and care fragmentation leading to repeat imaging and delayed biopsy in the eventual diagnosis of a rare illness.
Identifiants
pubmed: 30808157
doi: 10.1515/dx-2018-0096
pii: dx-2018-0096
doi:
Substances chimiques
Anti-Bacterial Agents
0
Immunologic Factors
0
Steroids
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
393-396Références
Barton LL, Feigin RD. Childhood cervical lymphadenitis: a reappraisal. J Pediatr 1974;84:846–52.
Dajani AS, Garcia RE, Wolinsky E. Etiology of cervical lymphadenitis in children. N Engl J Med 1963;268:1329–33.
Rosenberg TL, Nolder AR. Pediatric cervical lymphadenopathy. Otolaryngol Clin North Am 2014;47:721–31.
Weinstock MS, Patel NA, Smith LP. Pediatric cervical lymphadenopathy. Pediatr Rev 2018;39:433–43.
Mrówka-Kata K, Kata D, Kyrcz-Krzemień S, Helbig G. Kikuchi-Fujimoto and Kimura diseases: the selected, rare causes of neck lymphadenopathy. Eur Arch Otorhinolaryngol 2010;267:5–11.
Thomas J, Jayachandran NV, Chandrasekhara PK, Rajasekhar L, Narsimulu G. Kimura’s disease – an unusual cause of lymphadenopathy in children. Clin Rheumatol 2008;27:675–7.
Dixit MP, Scott KM, Bracamonte E, Dixit NM, Schumacher MJ, Hutter J, et al. Kimura disease with advanced renal damage with anti-tubular basement membrane antibody. Pediatr Nephrol 2004;19:1404–7.
Chen H, Thompson LD, Aguilera NS, Abbondanzo SL. Kimura disease: a clinicopathologic study of 21 cases. Am J Surg Pathol 2004;28:505–13.
Viswanatha B. Kimura’s disease in children: a 9 years prospective study. Int J Pediatr Otorhinolaryngol 2007;71:1521–5.
Miki H, Tsuboi H, Kaneko S, Takahashi H, Yokosawa M, Asashima H, et al. A case of refractory Kimura disease with a buccal bulky mass successfully treated with low-dose cyclosporine A: report and review of the literature. Allergol Int 2016;65:212–4.
Croskerry P. Achieving quality in clinical decision making: cognitive strategies and detection of bias. Acad Emerg Med 2002;9:1184–204.
Schmidt HG, Rikers RM. How expertise develops in medicine: knowledge encapsulation and illness script formation. Med Educ 2007;41:1133–9.
Singh H, Thomas EJ, Wilson L, Kelly PA, Pietz K, Elkeeb D, et al. Errors of diagnosis in pediatric practice: a multisite survey. Pediatrics 2010;126:70–9.