Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity.

Animals Cerebral Cortex / embryology Gene Expression Profiling Gene Expression Regulation, Developmental Gene Knock-In Techniques Hippocampus / physiopathology Memory / physiology Mice Mice, Knockout Neuronal Plasticity / genetics Neurons / physiology Neurotransmitter Agents / metabolism Prosencephalon / cytology Synaptic Potentials / genetics Synaptic Transmission Synaptic Vesicles / genetics Synaptotagmins / deficiency
development membrane trafficking memory mouse genetics neuron secretion synaptic plasticity synaptotagmin

Journal

Genes & development
ISSN: 1549-5477
Titre abrégé: Genes Dev
Pays: United States
ID NLM: 8711660

Informations de publication

Date de publication:
01 03 2019
Historique:
received: 27 08 2018
accepted: 21 12 2018
pubmed: 28 2 2019
medline: 30 3 2019
entrez: 28 2 2019
Statut: ppublish

Résumé

Synaptotagmin-11 (Syt11) is a Synaptotagmin isoform that lacks an apparent ability to bind calcium, phospholipids, or SNARE proteins. While human genetic studies have linked mutations in the

Identifiants

DOI: 10.1101/gad.320077.118 PMID: 30808661 PMC: PMC6411015
pubmed: 30808661
pii: gad.320077.118
doi: 10.1101/gad.320077.118
pmc: PMC6411015
doi:

Substances chimiques

Neurotransmitter Agents 0
Synaptotagmins 134193-27-4

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

365-376

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM117049
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH085776
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS087026
Pays : United States
Organisme : NINDS NIH HHS
ID : R56 NS087026
Pays : United States

Informations de copyright

© 2019 Shimojo et al.; Published by Cold Spring Harbor Laboratory Press.

Références

Biochemistry. 2000 Mar 21;39(11):2940-9
pubmed: 10715114
Nature. 2001 Mar 1;410(6824):41-9
pubmed: 11242035
J Biol Chem. 2002 Mar 8;277(10):7629-32
pubmed: 11739399
EMBO J. 2002 Feb 1;21(3):270-80
pubmed: 11823420
Cell. 2003 Feb 21;112(4):519-33
pubmed: 12600315
Hum Mol Genet. 2003 Oct 15;12(20):2587-97
pubmed: 12925569
Nat Struct Mol Biol. 2004 Sep;11(9):844-9
pubmed: 15311271
Hippocampus. 2004;14(8):964-74
pubmed: 15390175
Neuron. 2005 Oct 6;48(1):123-37
pubmed: 16202713
Science. 2005 Nov 4;310(5749):858-63
pubmed: 16272123
EMBO J. 2006 May 17;25(10):2039-50
pubmed: 16642042
Cell. 2006 Sep 22;126(6):1175-87
pubmed: 16990140
Genesis. 2006 Dec;44(12):611-21
pubmed: 17146780
J Cell Biol. 2007 Jan 1;176(1):113-24
pubmed: 17190793
J Neurosci. 2006 Dec 27;26(52):13493-504
pubmed: 17192432
Am J Med Genet B Neuropsychiatr Genet. 2007 Apr 5;144B(3):332-40
pubmed: 17192956
Neuron. 2007 May 24;54(4):567-81
pubmed: 17521570
Nature. 2007 Nov 29;450(7170):676-82
pubmed: 18046404
J Biol Chem. 1991 Jan 5;266(1):615-22
pubmed: 1840599
J Physiol. 2009 Mar 15;587(Pt 6):1169-78
pubmed: 19171650
Nat Neurosci. 2009 Jun;12(6):767-76
pubmed: 19448629
Biosci Rep. 2009 Aug;29(4):245-59
pubmed: 19500075
FEBS Lett. 2009 Dec 3;583(23):3784-95
pubmed: 19854182
J Biol Chem. 1991 Jan 5;266(1):623-9
pubmed: 1985919
Nat Rev Mol Cell Biol. 2009 Dec;10(12):877-84
pubmed: 19935670
Cell. 2011 Apr 15;145(2):300-11
pubmed: 21496647
J Neurophysiol. 2012 May;107(9):2430-41
pubmed: 22279193
J Neurosci. 2012 Apr 18;32(16):5398-413
pubmed: 22514304
Neuroscience. 2012 Dec 6;225:35-43
pubmed: 22960622
Cell. 2012 Nov 9;151(4):821-834
pubmed: 23141539
Neuropharmacology. 2014 Jan;76 Pt C:610-27
pubmed: 23791959
Neuron. 2013 Nov 20;80(4):947-59
pubmed: 24267651
J Clin Invest. 2014 Oct;124(10):4503-16
pubmed: 25244095
Neuron. 2014 Dec 3;84(5):1009-22
pubmed: 25467984
Cell Rep. 2015 May 19;11(7):1054-66
pubmed: 25959820
EMBO Rep. 2016 Jan;17(1):47-63
pubmed: 26589353
Nature. 2015 Dec 24;528(7583):510-6
pubmed: 26618866
J Neurol Sci. 2016 Mar 15;362:321-5
pubmed: 26944171
Nat Protoc. 2016 Dec;11(12):2515-2528
pubmed: 27854364
Glia. 2017 Oct;65(10):1656-1667
pubmed: 28686317
Nat Commun. 2018 Jan 8;9(1):81
pubmed: 29311685
Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2164-8
pubmed: 7892240
Cell. 1994 Nov 18;79(4):717-27
pubmed: 7954835
J Biol Chem. 1993 Dec 15;268(35):26386-90
pubmed: 8253763
Neuron. 1996 Jun;16(6):1137-45
pubmed: 8663990
J Biol Chem. 1997 May 30;272(22):14314-9
pubmed: 9162066
Nature. 1998 Feb 26;391(6670):892-6
pubmed: 9495341
Nature. 1998 Jul 9;394(6689):192-5
pubmed: 9671304

Auteurs

Masafumi Shimojo (M)

Department of Neuroscience, Scripps Research, La Jolla, California 92037, USA.
The Dorris Neuroscience, Scripps Research, La Jolla, California 92037, USA.

Joseph Madara (J)

Department of Neuroscience, Scripps Research, La Jolla, California 92037, USA.
The Dorris Neuroscience, Scripps Research, La Jolla, California 92037, USA.

Sandra Pankow (S)

Department of Molecular Medicine, Scripps Research, La Jolla, California 92037, USA.

Xinran Liu (X)

Department of Neuroscience, University of Texas Southwestern Medical Center at Dallas, Dallas 75235, Texas, USA.

John Yates (J)

Department of Molecular Medicine, Scripps Research, La Jolla, California 92037, USA.

Thomas C Südhof (TC)

Department of Neuroscience, University of Texas Southwestern Medical Center at Dallas, Dallas 75235, Texas, USA.
Department of Molecular and Cellular Physiology, Stanford University, Palo Alto, California 94035, USA.

Anton Maximov (A)

Department of Neuroscience, Scripps Research, La Jolla, California 92037, USA.
The Dorris Neuroscience, Scripps Research, La Jolla, California 92037, USA.
Department of Neuroscience, University of Texas Southwestern Medical Center at Dallas, Dallas 75235, Texas, USA.

Articles similaires

Evaluating the efficacy of telesurgery with dual console SSI Mantra Surgical Robotic System: experiment on animal model and clinical trials.

Sudhir Prem Srivastava, Vishwajyoti Pascual Srivastava, Avinesh Singh et al.
1.00
Robotic Surgical Procedures Animals Humans Telemedicine Models, Animal

Odour generalisation and detection dog training.

Lyn Caldicott, Thomas W Pike, Helen E Zulch et al.
1.00
Animals Odorants Dogs Generalization, Psychological Smell

FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR.

Minle Li, Xuan Chen, Pengfei Qu et al.
1.00
Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice

Use of organic material provided by an automatic enrichment device by weaner pigs and its influence on tail lesions.

Philipp Heseker, Jeanette Probst, Stefanie Ammer et al.
1.00
Animals Tail Swine Behavior, Animal Animal Husbandry

Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Analyse de profil d'expression de gènes › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes au cours du développement › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-in de gènes › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Télencéphale › Cerveau › Cortex cérébral › Hippocampe › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Mémoire › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Plasticité neuronale › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Cellules › Neurones › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Agents neuromédiateurs › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Transmission synaptique › Potentiels synaptiques › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système nerveux › Transmission synaptique › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Vésicules de transport › Vésicules de sécrétion › Vésicules synaptiques › Synaptotagmin-11 mediates a vesicle...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines du transport vésiculaire › Synaptotagmines › Synaptotagmin-11 mediates a vesicle...