Educational delay and attainment in persons with neurofibromatosis 1 in Denmark.


Journal

European journal of human genetics : EJHG
ISSN: 1476-5438
Titre abrégé: Eur J Hum Genet
Pays: England
ID NLM: 9302235

Informations de publication

Date de publication:
06 2019
Historique:
received: 24 05 2018
accepted: 24 01 2019
revised: 20 12 2018
pubmed: 2 3 2019
medline: 12 6 2020
entrez: 2 3 2019
Statut: ppublish

Résumé

Most research on psychosocial consequences of neurofibromatosis type 1 (NF1) has focused on the relationship between disease factors and cognitive functioning. NF1 may impair domains of learning and attention, resulting in low academic performance. This study is the first nationwide population-based cohort study to investigate educational attainment and delay in completing mandatory school by persons with NF1. Educational information was collected from 550 persons at the age of 30 (born 1965-1984). They were diagnosed with NF1 in Denmark and compared to a cohort of NF1-free persons matched on gender and age (n = 4295). Multinomial logistic models were applied to estimate odds ratios (ORs) for obtaining short (≤9 years) or medium (10-12 years) education compared to long education (>12 years) by the age of 30 years. We calculated the probability of graduating 9

Identifiants

pubmed: 30820037
doi: 10.1038/s41431-019-0359-8
pii: 10.1038/s41431-019-0359-8
pmc: PMC6777448
doi:

Types de publication

Journal Article Randomized Controlled Trial Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

857-868

Commentaires et corrections

Type : ErratumIn

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Auteurs

Karoline Doser (K)

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark. kdoser@cancer.dk.

Line Kenborg (L)

Childhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.

Elisabeth Wreford Andersen (EW)

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.

Pernille Envold Bidstrup (PE)

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.

Anja Kroyer (A)

Childhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.

Hanne Hove (H)

The RAREDIS Database, Centre for Rare Diseases, Copenhagen University Hospital and Aarhus University, Aarhus, Denmark.

John Østergaard (J)

Center for Rare Disease, Aarhus University Hospital, Aarhus, Denmark.

Sven Asger Sørensen (SA)

Copenhagen University, Copenhagen, Denmark.

Christoffer Johansen (C)

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.
Oncology Clinic, Finsen Center, Rigshospitalet, 5073, Copenhagen, Denmark.

John Mulvihill (J)

University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

Jeanette Falck Winther (JF)

Childhood Cancer Research Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
Department of Clinical Medicine, Faculty of Health, Aarhus University, Aarhus, Denmark.

Susanne Oksbjerg Dalton (SO)

Survivorship Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.

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Classifications MeSH