Recent advances in understanding biliary atresia.


Journal

F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320

Informations de publication

Date de publication:
2019
Historique:
accepted: 19 02 2019
entrez: 5 3 2019
pubmed: 5 3 2019
medline: 4 6 2020
Statut: epublish

Résumé

Biliary atresia (BA) is a neonatal liver disease characterized by progressive obstruction and fibrosis of the extrahepatic biliary tree as well as fibrosis and inflammation of the liver parenchyma. Recent studies found that infants who will go on to develop BA have elevated direct bilirubin levels in the first few days of life, suggesting that the disease starts

Identifiants

pubmed: 30828434
doi: 10.12688/f1000research.16732.1
pmc: PMC6392153
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIEHS NIH HHS
ID : P30 ES013508
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK119290
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK101371
Pays : United States

Déclaration de conflit d'intérêts

No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

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Auteurs

Andrew Wehrman (A)

Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.

Orith Waisbourd-Zinman (O)

Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA.
Gastroenterology, Hepatology, and Nutrition, Schneider Children's Medical Center of Israel, Petach-Tiqva, Israel.

Rebecca G Wells (RG)

Medicine and Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.

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Classifications MeSH