Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery.
Biliary atresia
Dental pulp
Diaphragm
Mesenchymal stem cell
Primary teeth
Journal
Surgery today
ISSN: 1436-2813
Titre abrégé: Surg Today
Pays: Japan
ID NLM: 9204360
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
19
09
2018
accepted:
07
02
2019
pubmed:
6
3
2019
medline:
4
4
2019
entrez:
6
3
2019
Statut:
ppublish
Résumé
Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.
Identifiants
pubmed: 30834983
doi: 10.1007/s00595-019-01783-z
pii: 10.1007/s00595-019-01783-z
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
316-322Références
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