An Observational Study on the Use of Intravenous Non-Opioid Analgesics and Antipyretics in Poor-Grade Subarachnoid Hemorrhage: Effects on Hemodynamics and Systemic and Brain Temperature.
Aged
Analgesics, Non-Narcotic
/ administration & dosage
Antipyretics
/ administration & dosage
Body Temperature
/ physiology
Cerebrovascular Circulation
/ drug effects
Dose-Response Relationship, Drug
Female
Follow-Up Studies
Humans
Hypothermia, Induced
/ methods
Injections, Intravenous
Intracranial Pressure
/ drug effects
Male
Middle Aged
Prospective Studies
Subarachnoid Hemorrhage
/ drug therapy
antipyretics
subarachnoid hemorrhage
Journal
Therapeutic hypothermia and temperature management
ISSN: 2153-7933
Titre abrégé: Ther Hypothermia Temp Manag
Pays: United States
ID NLM: 101543518
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
pubmed:
6
3
2019
medline:
15
12
2020
entrez:
6
3
2019
Statut:
ppublish
Résumé
Intravenous nonsteroidal anti-inflammatory drugs and nonopioid analgesics are used to achieve normothermia or relieve pain in patients with aneurysmal subarachnoid hemorrhage (aSAH). We investigated the effects of paracetamol (1 g), diclofenac (75 mg) and metamizole (1 g) on systemic and cerebral hemodynamics and temperature during febrile and nonfebrile episodes after aSAH. Prospectively collected data from 77 consecutive poor-grade aSAH patients with invasive neuromonitoring were included. The burden and occurrence of hypotension (mean arterial pressure <70 mmHg), brain tissue hypoxia (P
Identifiants
pubmed: 30835164
doi: 10.1089/ther.2018.0046
doi:
Substances chimiques
Analgesics, Non-Narcotic
0
Antipyretics
0
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
27-36Subventions
Organisme : Austrian Science Fund FWF
ID : P 29076
Pays : Austria