High-Temperature Spray-Dried Polymer/Bacteria Microparticles for Electrospinning of Composite Nonwovens.


Journal

Macromolecular bioscience
ISSN: 1616-5195
Titre abrégé: Macromol Biosci
Pays: Germany
ID NLM: 101135941

Informations de publication

Date de publication:
05 2019
Historique:
received: 19 09 2018
revised: 15 02 2019
pubmed: 7 3 2019
medline: 28 11 2019
entrez: 7 3 2019
Statut: ppublish

Résumé

Living Micrococcus luteus (M. luteus) and Escherichia coli (E. coli) are encapsulated in poly(vinyl alcohol), poly(vinylpyrrolidone), hydroxypropyl cellulose, and gelatin by high-temperature spray drying. The challenge is the survival of the bacteria during the standard spray-drying process at temperatures of 150 °C (M. luteus) and 120 °C (E. coli). Raman imaging and transmission electron microscopy indicate encapsulated bacteria in hollow composite microparticles. The versatility of the spray-dried polymer bacteria microparticles is successfully proved by standard polymer solution-processing techniques such as electrospinning, even with harmful solvents, to water-insoluble polyacrylonitrile, polystyrene, poly(methyl methacrylate), and poly(vinyl butyrate) nanofiber nonwovens, which opens numerous new opportunities for novel applications.

Identifiants

pubmed: 30840362
doi: 10.1002/mabi.201800356
doi:

Substances chimiques

Polymers 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e1800356

Subventions

Organisme : Deutsche Forschungsgemeinschaft
ID : GIP
Pays : International
Organisme : Bayerisches Staatsministerium für Umwelt und Verbraucherschutz
ID : Baybiotech
Pays : International

Informations de copyright

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Auteurs

Steffen Reich (S)

Macromolecular Chemistry and Bavarian Polymer Institute, University of Bayreuth, D-95440, Bayreuth, Germany.

Patrick Kaiser (P)

Chair for Process Biotechnology, University of Bayreuth, 95447, Bayreuth, Germany.

Mahsa Mafi (M)

Macromolecular Chemistry and Bavarian Polymer Institute, University of Bayreuth, D-95440, Bayreuth, Germany.

Holger Schmalz (H)

Macromolecular Chemistry and Bavarian Polymer Institute, University of Bayreuth, D-95440, Bayreuth, Germany.

Daniel Rhinow (D)

Department of Structural Biology, Max Planck Institute of Biophysics, D-60438, Frankfurt am Main, Germany.

Ruth Freitag (R)

Chair for Process Biotechnology, University of Bayreuth, 95447, Bayreuth, Germany.

Andreas Greiner (A)

Macromolecular Chemistry and Bavarian Polymer Institute, University of Bayreuth, D-95440, Bayreuth, Germany.

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