Revised FRAX®-based intervention thresholds for the management of osteoporosis among postmenopausal women in Sri Lanka.
Absorptiometry, Photon
/ statistics & numerical data
Aged
Aged, 80 and over
Algorithms
Bone Density
Decision Support Techniques
Female
Hip Fractures
/ epidemiology
Humans
Middle Aged
Osteoporosis, Postmenopausal
/ complications
Osteoporotic Fractures
/ epidemiology
Pelvic Bones
/ diagnostic imaging
Postmenopause
ROC Curve
Reference Standards
Risk Assessment
/ methods
Risk Factors
Sensitivity and Specificity
Sri Lanka
/ epidemiology
FRAX
Hybrid
Intervention thresholds
Sri Lanka
Journal
Archives of osteoporosis
ISSN: 1862-3514
Titre abrégé: Arch Osteoporos
Pays: England
ID NLM: 101318988
Informations de publication
Date de publication:
09 03 2019
09 03 2019
Historique:
received:
30
01
2019
accepted:
01
03
2019
entrez:
10
3
2019
pubmed:
10
3
2019
medline:
24
3
2020
Statut:
epublish
Résumé
This paper revised the fixed intervention thresholds (ITs) based on the Sri Lankan fracture risk assessment tool (FRAX) published in 2013 and introduced new ITs, hybrid and two-tier, aiming to help clinicians in the management of postmenopausal osteoporosis. The hybrid and two-tier ITs have a better discriminatory power than age-dependent and revised fixed ITs. This study revised the Sri Lankan FRAX®-based intervention thresholds (ITs) previously published in 2013. Age-dependent ITs were estimated, from 50-80 years with 5-year intervals, using a Sri Lankan FRAX® algorithm for a woman with a BMI of 24.8 kg/m The mean (SD) age and BMI of the subjects (n = 653) were 62 (8) years and 24.8 (1.2) kg/m The new fixed MOFR is slightly lower than the previous value and hybrid and two-tier ITs perform better than age-dependent and fixed ITs.
Identifiants
pubmed: 30850909
doi: 10.1007/s11657-019-0585-2
pii: 10.1007/s11657-019-0585-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM