Evolution of fetal lung stiffness during gestation in two different congenital malformations.
congenital malformation
lung pathology
prenatal imaging
stiffness
Journal
The journal of obstetrics and gynaecology research
ISSN: 1447-0756
Titre abrégé: J Obstet Gynaecol Res
Pays: Australia
ID NLM: 9612761
Informations de publication
Date de publication:
Apr 2019
Apr 2019
Historique:
received:
27
05
2018
accepted:
30
11
2018
pubmed:
12
3
2019
medline:
15
8
2019
entrez:
12
3
2019
Statut:
ppublish
Résumé
This report is aimed at opening a new reflexion about exploration of fetal lungs malformations with 2-D ultrasound shear wave elastography (2D-SWE) in two fetuses. These preliminary results are drawn from the ELASTOMAP study, which was designed to explore feasibility of 2D-SWE on fetal lungs. Fetus A presented Congenital Pulmonary Airway Malformation and fetus B congenital obstructive emphysema. We estimated every 3 weeks the Congenital Pulmonary Airway Malformation Volume Ratio (CVR) of the malformation and we evaluated stiffness by 2D-SWE. Stiffness of the lesion and the normal lung were compared to liver stiffness using Lung to Liver Elastography (LLE) ratio. Interestingly, CVR and LLE ratios evolved differently in these two lesions caused by distinct physiopathological processes. In both cases, LLE ratio' variations preceded that of CVR. LLE ratio of the normal lung was constant through gestation. 2D-SWE could be a promising tool to describe stiffness evolution in fetal lungs malformations.
Types de publication
Case Reports
Langues
eng
Pagination
931-934Informations de copyright
© 2019 Japan Society of Obstetrics and Gynecology.