Local edge-enhanced active contour for accurate skin lesion border detection.


Journal

BMC bioinformatics
ISSN: 1471-2105
Titre abrégé: BMC Bioinformatics
Pays: England
ID NLM: 100965194

Informations de publication

Date de publication:
14 Mar 2019
Historique:
entrez: 16 3 2019
pubmed: 16 3 2019
medline: 3 5 2019
Statut: epublish

Résumé

Dermoscopy is one of the common and effective imaging techniques in diagnosis of skin cancer, especially for pigmented lesions. Accurate skin lesion border detection is the key to extract important dermoscopic features of the skin lesion. In current clinical settings, border delineation is performed manually by dermatologists. Operator based assessments lead to intra- and inter-observer variations due to its subjective nature. Moreover it is a tedious process. Because of aforementioned hurdles, the automation of lesion boundary detection in dermoscopic images is necessary. In this study, we address this problem by developing a novel skin lesion border detection method with a robust edge indicator function, which is based on a meshless method. Our results are compared with the other image segmentation methods. Our skin lesion border detection algorithm outperforms other state-of-the-art methods. Based on dermatologist drawn ground truth skin lesion borders, the results indicate that our method generates reasonable boundaries than other prominent methods having Dice score of 0.886 ±0.094 and Jaccard score of 0.807 ±0.133. We prove that smoothed particle hydrodynamic (SPH) kernels can be used as edge features in active contours segmentation and probability map can be employed to avoid the evolving contour from leaking into the object of interest.

Sections du résumé

BACKGROUND BACKGROUND
Dermoscopy is one of the common and effective imaging techniques in diagnosis of skin cancer, especially for pigmented lesions. Accurate skin lesion border detection is the key to extract important dermoscopic features of the skin lesion. In current clinical settings, border delineation is performed manually by dermatologists. Operator based assessments lead to intra- and inter-observer variations due to its subjective nature. Moreover it is a tedious process. Because of aforementioned hurdles, the automation of lesion boundary detection in dermoscopic images is necessary. In this study, we address this problem by developing a novel skin lesion border detection method with a robust edge indicator function, which is based on a meshless method.
RESULT RESULTS
Our results are compared with the other image segmentation methods. Our skin lesion border detection algorithm outperforms other state-of-the-art methods. Based on dermatologist drawn ground truth skin lesion borders, the results indicate that our method generates reasonable boundaries than other prominent methods having Dice score of 0.886 ±0.094 and Jaccard score of 0.807 ±0.133.
CONCLUSION CONCLUSIONS
We prove that smoothed particle hydrodynamic (SPH) kernels can be used as edge features in active contours segmentation and probability map can be employed to avoid the evolving contour from leaking into the object of interest.

Identifiants

pubmed: 30871471
doi: 10.1186/s12859-019-2625-8
pii: 10.1186/s12859-019-2625-8
pmc: PMC6419326
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

91

Subventions

Organisme : NIBIB NIH HHS
ID : R01 EB025241
Pays : United States

Références

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pubmed: 20801742
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pubmed: 26589251
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pubmed: 19121917
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pubmed: 18616769
IEEE Trans Image Process. 2007 Apr;16(4):1046-57
pubmed: 17405436
BMC Bioinformatics. 2010 Oct 07;11 Suppl 6:S23
pubmed: 20946607
Am J Surg Pathol. 2012 Jan;36(1):e1-5
pubmed: 22173121
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pubmed: 15691255
Med Image Anal. 2010 Feb;14(1):13-20
pubmed: 19828356
Br J Gen Pract. 2013 May;63(610):e345-53
pubmed: 23643233
IEEE Trans Image Process. 2013 Jan;22(1):258-71
pubmed: 22910114
J Am Acad Dermatol. 1994 Apr;30(4):551-9
pubmed: 8157780

Auteurs

Mustafa Bayraktar (M)

Bioinformatics, University of Arkansas Little Rock, 2804 S. University, Little Rock, 72204, AR, USA.

Sinan Kockara (S)

Computer Science, University of Central Arkansas, 201 Donaghey Avenue, Conway, 72035, AR, USA. skockara@uca.edu.

Tansel Halic (T)

Computer Science, University of Central Arkansas, 201 Donaghey Avenue, Conway, 72035, AR, USA.

Mutlu Mete (M)

Computer Science, Texas A&M University-Commerce, 2200 Campbell, Commerce, 75428, TX, USA.

Henry K Wong (HK)

Dermatology, University of Arkansas for Medical Sciences, 324 Campus Dr., Little Rock, 72205, AR, USA.

Kamran Iqbal (K)

Systems Engineering, University of Arkansas for Medical Sciences, 2804 S. University, Little Rock, 72204, AR, USA.

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Classifications MeSH