Sutureless amniotic membrane transplantation with cyanoacrylate glue for acute Stevens-Johnson syndrome/toxic epidermal necrolysis.


Journal

The ocular surface
ISSN: 1937-5913
Titre abrégé: Ocul Surf
Pays: United States
ID NLM: 101156063

Informations de publication

Date de publication:
07 2019
Historique:
received: 10 01 2019
revised: 05 03 2019
accepted: 05 03 2019
pubmed: 16 3 2019
medline: 20 9 2020
entrez: 16 3 2019
Statut: ppublish

Résumé

Amniotic membrane (AM) transplantation, when performed in the acute phase in Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) for patients with ocular complications, is known to reduce the morbidity of ocular complications in the chronic phase. In conditions such as SJS/TEN, AM needs to be secured to the ocular surface as well as the eyelids. Previously, techniques of securing a large sheet of AM with fibrin glue to the ocular surface and with sutures and bolsters to the eyelids have been described in the acute phase of SJS/TEN. These techniques often necessitate the use of an operating room in acutely ill patients. We describe a bedside technique that uses cyanoacrylate glue to secure the AM to the eyelids, as well as long-term outcomes in 4 patients with acute SJS/TEN. The combination of a custom symblepharon ring to secure AM over the entire ocular surface and cyanoacrylate glue to secure AM to the eyelid margins is quick, painless, does not require local or general anesthesia, and might prove useful in other conditions previously shown to benefit from AMT, such as ocular chemical injuries.

Identifiants

pubmed: 30872140
pii: S1542-0124(19)30010-2
doi: 10.1016/j.jtos.2019.03.001
pmc: PMC7811360
mid: NIHMS1025524
pii:
doi:

Substances chimiques

Cyanoacrylates 0

Types de publication

Case Reports Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

560-564

Subventions

Organisme : NEI NIH HHS
ID : K23 EY028230
Pays : United States

Informations de copyright

Copyright © 2019. Published by Elsevier Inc.

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Auteurs

Swapna S Shanbhag (SS)

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

James Chodosh (J)

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

Hajirah N Saeed (HN)

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA. Electronic address: Hajirah_Saeed@meei.harvard.edu.

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Classifications MeSH