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Syndrome de Stevens-Johnson
Syndrome de Stevens-Johnson : Questions médicales fréquentes
Diagnostic
5
Syndrome de Stevens-Johnson
Diagnostic médical
Biopsie
Syndrome de Stevens-Johnson
Lésions cutanées
Syndrome de Stevens-Johnson
Pemphigus
Syndrome de Stevens-Johnson
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Syndrome de Stevens-Johnson
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5
Fièvre
Syndrome de Stevens-Johnson
Lésions cutanées
Vésicules
Conjonctivite
Syndrome de Stevens-Johnson
Muqueuses
Syndrome de Stevens-Johnson
Symptômes respiratoires
Syndrome de Stevens-Johnson
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5
Tests génétiques
Syndrome de Stevens-Johnson
Allergies
Syndrome de Stevens-Johnson
Médicaments
Syndrome de Stevens-Johnson
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5
Traitement
Syndrome de Stevens-Johnson
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Syndrome de Stevens-Johnson
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Immunosuppresseurs
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Syndrome de Stevens-Johnson
Complications
5
Mortalité
Syndrome de Stevens-Johnson
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Syndrome de Stevens-Johnson
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Syndrome de Stevens-Johnson
Facteurs de risque
5
Facteurs de risque
Médicaments
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Maladies auto-immunes
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Infections
Syndrome de Stevens-Johnson
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"text": "Le diagnostic repose sur l'examen clinique et l'historique médical du patient."
}
},
{
"@type": "Question",
"name": "Quels tests sont nécessaires pour le diagnostic ?",
"position": 2,
"acceptedAnswer": {
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}
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"name": "Quels signes cliniques indiquent ce syndrome ?",
"position": 3,
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}
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"@type": "Question",
"name": "Le syndrome peut-il être confondu avec d'autres maladies ?",
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"@type": "Question",
"name": "Quels sont les symptômes initiaux du syndrome ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes initiaux incluent fièvre, douleurs corporelles et éruption cutanée."
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"@type": "Question",
"name": "Comment se manifestent les lésions cutanées ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les lésions apparaissent sous forme de vésicules et de croûtes sur la peau."
}
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"@type": "Question",
"name": "Y a-t-il des symptômes oculaires associés ?",
"position": 8,
"acceptedAnswer": {
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}
},
{
"@type": "Question",
"name": "Les muqueuses sont-elles affectées ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les muqueuses buccales et génitales peuvent être gravement touchées."
}
},
{
"@type": "Question",
"name": "Peut-on avoir des symptômes respiratoires ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes respiratoires peuvent survenir, mais ils sont moins fréquents."
}
},
{
"@type": "Question",
"name": "Comment prévenir le syndrome de Stevens-Johnson ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les médicaments connus pour déclencher le syndrome est essentiel."
}
},
{
"@type": "Question",
"name": "Les tests génétiques peuvent-ils aider ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains tests génétiques peuvent identifier des risques accrus pour certains médicaments."
}
},
{
"@type": "Question",
"name": "Faut-il informer les médecins de ses allergies ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, informer les médecins de toutes les allergies médicamenteuses est crucial."
}
},
{
"@type": "Question",
"name": "Les vaccinations peuvent-elles aider à prévenir ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les vaccinations ne préviennent pas le syndrome, mais protègent contre d'autres infections."
}
},
{
"@type": "Question",
"name": "Comment gérer les médicaments à risque ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Discutez avec votre médecin des alternatives aux médicaments à risque connu."
}
},
{
"@type": "Question",
"name": "Quel est le traitement principal du syndrome ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le traitement principal consiste à arrêter le médicament responsable et à gérer les symptômes."
}
},
{
"@type": "Question",
"name": "Des soins hospitaliers sont-ils nécessaires ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une hospitalisation est souvent nécessaire pour surveiller et traiter les complications."
}
},
{
"@type": "Question",
"name": "Quels médicaments peuvent être utilisés ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des corticostéroïdes et des immunosuppresseurs peuvent être prescrits dans certains cas."
}
},
{
"@type": "Question",
"name": "Comment traiter les douleurs associées ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des analgésiques peuvent être administrés pour soulager les douleurs corporelles."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements topiques recommandés ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des soins topiques pour les lésions cutanées peuvent aider à prévenir l'infection."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications possibles ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des infections, des cicatrices et des atteintes oculaires."
}
},
{
"@type": "Question",
"name": "Le syndrome peut-il être mortel ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le syndrome de Stevens-Johnson peut être fatal dans les cas graves."
}
},
{
"@type": "Question",
"name": "Comment les infections sont-elles gérées ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections sont traitées avec des antibiotiques et des soins appropriés."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de complications à long terme ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications à long terme comme des problèmes oculaires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Les cicatrices sont-elles fréquentes ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des cicatrices peuvent se former, surtout si les lésions cutanées étaient étendues."
}
},
{
"@type": "Question",
"name": "Quels sont les principaux facteurs de risque ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les principaux facteurs incluent l'utilisation de certains médicaments et des infections virales."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux jouent-ils un rôle ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de réactions cutanées peuvent augmenter le risque."
}
},
{
"@type": "Question",
"name": "Les maladies auto-immunes sont-elles un facteur ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les maladies auto-immunes peuvent augmenter le risque de développer le syndrome."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les jeunes adultes et les personnes âgées sont plus à risque."
}
},
{
"@type": "Question",
"name": "Les infections antérieures augmentent-elles le risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections, comme le VIH, peuvent augmenter le risque de syndrome."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 28/07/2026
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
CJ Shah Cornea Services, Dr. G. Sitalakshmi Memorial Clinic for Ocular Surface Disorders, Medical Research Foundation, Sankara Nethralaya, Chennai, India.
Publications dans "Syndrome de Stevens-Johnson" :
3 publications dans cette catégorie
Publications dans "Syndrome de Stevens-Johnson" :
3 publications dans cette catégorie
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
Department of Ophthalmology, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Hirokoji-agaru, Kawaramachi-dori, Kamigyo-ku, Kyoto, 602-0841, Japan.
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Publications dans "Syndrome de Stevens-Johnson" :
2 publications dans cette catégorie
Affiliations :
R. S. Mehta Jain Department of Biochemistry and Cell Biology, Vision Research Foundation, Sankara Nethralaya, Chennai, India drak@snmail.org drgki@snmail.org.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Division of Community Pediatrics, Department of Pediatrics, Alberta Children's Hospital.
Division of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Department of Surgery, Massachusetts General Hospital, Sumner Redstone Burn Center, Boston, MA, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, MA, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Family and Community Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Family Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Family and Community Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Family Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Publications dans "Syndrome de Stevens-Johnson" :
1 publication dans cette catégorie
Affiliations :
Family and Community Medicine, Southern Illinois University School of Medicine, Springfield, USA.
Publications dans "Syndrome de Stevens-Johnson" :
BACKGROUND Stevens-Johnson syndrome (SJS) is a rare dermatologic disorder that is characterized by nonspecific flu-like prodrome with fever, malaise, myalgia, cough, rhinitis, and sore eyes, followed ...
To summarize the outcomes of corneal sight rehabilitating surgery in Stevens-Johnson syndrome (SJS)....
This is a retrospective analysis of a consecutive case series. Twenty-four eyes of 18 SJS patients were included in this study. The ocular parameters, surgical procedures, postoperative complications,...
A total of 29 corneal sight rehabilitating surgeries, which consists of 9 keratoplasties, 8 Keratolimbal allograft (KLAL) and 12 combined surgeries (keratoplasty and KLAL simultaneously) were performe...
Keratoplasty and KLAL can remarkably enhance VA and improve low vision or even eliminate blindness for ocular complications of SJS. The outcome of the surgeries was correlated with the preoperative oc...
A severe medical condition known as Stevens-Johnson syndrome (SJS) is marked by a cutaneous and mucosal reaction from the use of specific medications. The prodromal illness is followed by severe mucoc...
Severe cutaneous adverse drug reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are challenging to be early diagnosed and evaluate their prognoses. This investi...
Severe cutaneous adverse reactions (SCARs) arising from drug interactions can carry life-threatening implications and result in lasting effects. SCARs can be triggered by various factors, with trimeth...
We present the case of a three-year-old male patient diagnosed with ALL who developed Stevens-Johnson syndrome (SJS) subsequent to the administration of MTX, following the "BFM 2009" protocol. He had ...
As far as we know, the prophylactic use of IVIG to counteract SCARs in a pediatric leukemia patient represents uncharted territory. Moreover, research into the immune system dynamics within these pati...
Stevens-Johnson syndrome-toxic epidermal necrolysis (SJS-TNE) overlap is a rare skin disorder characterized by erythema, blisters, extensive exfoliation, epidermal detachment, the involvement of multi...
An 82-year-old Taiwanese female was admitted to our hospital for decreased urine output, generalized edema, and multiple skin blisters and bedsores. With further spread of the lesions, multiple ruptur...
Stevens-Johnson syndrome-toxic epidermal necrolysis is a rare skin disorder. Although it is mainly acute and has a high mortality rate, delayed onset can still occur. Quetiapine and famotidine are gen...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare yet life-threatening adverse events associated with immune checkpoint inhibitors (ICIs). This systematic review synthesizes...
We conducted a thorough search across databases including Embase, Web of Science, Cochrane, MEDLINE, Scopus, and PubMed. Selection criteria focused on reports of SJS/TEN among cancer patients treated ...
Our analysis included 47 articles involving 50 patients with ICI-related SJS/TEN. The cohort had a mean age of 63 years, with a slight male predominance (54%). Most patients had melanoma or non-small ...
ICI-related SJS/TEN substantially impacts patient outcomes. Prospective clinical trials are critically needed to further clarify the pathogenesis and optimize therapeutic regimens....
Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen (HLA) class I-restricted CD8...
Stevens-Johnson syndrome (SJS) is a life-threatening condition characterized by high fever and severe mucocutaneous lesions, often triggered by drugs or infection. During the coronavirus disease 2019 ...
A previously healthy 15-year-old Han Chinese boy from China presented to the hospital with oral ulcers, conjunctival hyperemia, and widespread maculopapular rash. He had a history of fever 9 days prio...
We should be aware that coronavirus disease 2019 infection is associated with the development of Stevens-Johnson syndrome in children and may lead to a wide spectrum of dermatologic presentations. Alt...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but life-threatening skin lesion triggered by hypersensitive drug reaction. They are characterized by extensive epidermal n...
We present a 73-year-old female patient who developed SJS/TEN skin allergic reaction after taking carbamazepine and phenytoin for 35 days. Then, hyperglycemia and diabetic ketoacidosis occurred 20 day...
This rare case indicates that monitoring blood glucose is necessary in SJS/TEN drug reaction, and comprehensive therapy with rehydration, insulin, antibiotics, and IVIG may improve the prognosis....