Stevens-Johnson syndrome: a case report of possible cephalosporin-induced cutaneous adverse reaction.

Naranjo scale Stevens-Johnson syndrome cephalosporins scarlet fever severe cutaneous adverse reaction

Journal

Journal of infection in developing countries
ISSN: 1972-2680
Titre abrégé: J Infect Dev Ctries
Pays: Italy
ID NLM: 101305410

Informations de publication

Date de publication:
31 10 2023
Historique:
received: 02 04 2023
accepted: 07 06 2023
medline: 15 11 2023
pubmed: 13 11 2023
entrez: 13 11 2023
Statut: epublish

Résumé

A severe medical condition known as Stevens-Johnson syndrome (SJS) is marked by a cutaneous and mucosal reaction from the use of specific medications. The prodromal illness is followed by severe mucocutaneous symptoms in this immune-mediated disease. We describe the clinical history of a 55-year-old Caucasian woman who was exposed to cephalosporins. In resource-constrained countries and hospitals where cutaneous biopsy is not readily available, it is not easy to diagnose Steven Johnson Syndrome. This is particularly true in countries where the incidence of infectious diseases such as scarlet fever and measles is high and the early symptoms of SJS can be mistaken for these conditions. We used the Naronjo scale to confirm the probable association of the drug with the syndrome. Physicians while writing prescriptions for their patients need to warn them of potential side effects and they should keep in mind conditions like Stevens-Johnson syndrome. This case report highlights the need for improved knowledge and understanding of SJS among healthcare practitioners in resource-limited communities where the prevalence of infectious diseases is high.

Identifiants

pubmed: 37956371
doi: 10.3855/jidc.18301
doi:

Substances chimiques

Cephalosporins 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1493-1496

Informations de copyright

Copyright (c) 2023 Anna Mkhoyan, Md. Foorquan Hashmi, Fiza Khan, Naira Gyulazyan, Vigen Asoyan, Varsen Nersisyan.

Déclaration de conflit d'intérêts

No Conflict of Interest is declared

Auteurs

Anna Mkhoyan (A)

Department of Infectious Diseases, Yerevan State Medical University, Yerevan, Armenia.

Md Foorquan Hashmi (MF)

General Medicine, Yerevan State Medical University, Yerevan, Armenia.

Fiza Khan (F)

General Medicine, Yerevan State Medical University, Yerevan, Armenia.

Naira Gyulazyan (N)

Department of Infectious Diseases, Yerevan State Medical University, Yerevan, Armenia.

Vigen Asoyan (V)

Department of Infectious Diseases, Yerevan State Medical University, Yerevan, Armenia.

Varsen Nersisyan (V)

National Centre for Infectious Diseases, Yerevan, Armenia.

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