Selectivity in multiple multicomponent reactions: types and synthetic applications.
isocyanides
multicomponent reactions
reaction discovery
selectivity
Journal
Beilstein journal of organic chemistry
ISSN: 1860-5397
Titre abrégé: Beilstein J Org Chem
Pays: Germany
ID NLM: 101250746
Informations de publication
Date de publication:
2019
2019
Historique:
received:
13
12
2018
accepted:
07
02
2019
entrez:
16
3
2019
pubmed:
16
3
2019
medline:
16
3
2019
Statut:
epublish
Résumé
Multiple multicomponent reactions reach an unparalleled level of connectivity, leading to highly complex adducts. Usually, only one type of transformation involving the same set of reactants takes place. However, in some occasions this is not the case. Selectivity issues then arise, and different scenarios are analyzed. The structural pattern of the reactants, the reaction design and the experimental conditions are the critical factors dictating selectivity in these processes.
Identifiants
pubmed: 30873236
doi: 10.3762/bjoc.15.46
pmc: PMC6404517
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
521-534Références
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