Rodolfo Lavilla

Affiliations

Laboratory of Medicinal Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain.

Publications (21)

Multicomponent Reactions Upon the Known Drug Trimethoprim as a Source of Novel Antimicrobial Agents.

Frontiers in chemistry

Avec: Marina Pedrola , Marta Jorba , Eda Jardas , Ferran Jardi , Ouldouz Ghashghaei , Miguel Viñas , Rodolfo Lavilla

A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.

Angewandte Chemie (International ed. in English)

Avec: Nicole D Barth , Lorena Mendive-Tapia , Ramon Subiros-Funosas , Ouldouz Ghashghaei , Rodolfo Lavilla , Laura Maiorino , Xue-Yan He , Ian Dransfield , Mikala Egeblad , Marc Vendrell

Activation of the Integrated Stress Response and ER Stress Protect from Fluorizoline-Induced Apoptosis in HEK293T and U2OS Cell Lines.

International journal of molecular sciences

Avec: José Saura-Esteller , Ismael Sánchez-Vera , Sonia Núñez-Vázquez , Ana M Cosialls , Pau Gama-Pérez , Gauri Bhosale , Lorena Mendive-Tapia , Rodolfo Lavilla , Gabriel Pons , Pablo M Garcia-Roves , Michael R Duchen , Daniel Iglesias-Serret , Joan Gil

A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging.

RSC chemical biology

Avec: Antonio Fernandez , Nicola Kielland , Ashraff Makda , Neil O Carragher , M Carmen González-García , Laura Espinar-Barranco , Juan A González-Vera , Angel Orte , Rodolfo Lavilla , Marc Vendrell

Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants.

ACS central science

Avec: Marco Bertolini , Lorena Mendive-Tapia , Ouldouz Ghashghaei , Abigail Reese , Charles Lochenie , Anna M Schoepf , Miquel Sintes , Karolina Tokarczyk , Zandile Nare , Andrew D Scott , Stephen R Knight , Advait R Aithal , Amit Sachdeva , Rodolfo Lavilla , Marc Vendrell

Efficient AntiMycolata Agents by Increasing the Lipophilicity of Known Antibiotics through Multicomponent Reactions.

Antibiotics (Basel, Switzerland)

Avec: Angela Trejo , Carme Masdeu , Irene Serrano-Pérez , Marina Pedrola , Narcís Juanola , Ouldouz Ghashghaei , Guadalupe Jiménez-Galisteo , Rodolfo Lavilla , Francisco Palacios , Concepción Alonso , Miguel Viñas

The Prohibitin-Binding Compound Fluorizoline Activates the Integrated Stress Response through the eIF2α Kinase HRI.

International journal of molecular sciences

Avec: Ismael Sánchez-Vera , Sonia Núñez-Vázquez , José Saura-Esteller , Ana M Cosialls , Judith Heib , Pau Nadal Rodríguez , Ouldouz Ghashghaei , Rodolfo Lavilla , Gabriel Pons , Joan Gil , Daniel Iglesias-Serret

The BCL-2 family members NOXA and BIM mediate fluorizoline-induced apoptosis in multiple myeloma cells.

Biochemical pharmacology

Avec: Ana M Cosialls , Ismael Sánchez-Vera , Helena Pomares , Judit Perramon-Andújar , Sandra Sanchez-Esteban , Claudia M Palmeri , Daniel Iglesias-Serret , José Saura-Esteller , Sonia Núñez-Vázquez , Rodolfo Lavilla , Eva M González-Barca , Gabriel Pons , Joan Gil

Selectivity in multiple multicomponent reactions: types and synthetic applications.

Beilstein journal of organic chemistry

Avec: Ouldouz Ghashghaei , Francesca Seghetti , Rodolfo Lavilla

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis.

Nature communications

Avec: Nicole D Barth , Ramon Subiros-Funosas , Lorena Mendive-Tapia , Rodger Duffin , Mario A Shields , Jennifer A Cartwright , Sónia Troeira Henriques , Jesus Sot , Felix M Goñi , Rodolfo Lavilla , John A Marwick , Sonja Vermeren , Adriano G Rossi , Mikala Egeblad , Ian Dransfield , Marc Vendrell

Fluorizoline-induced apoptosis requires prohibitins in nematodes and human cells.

Apoptosis : an international journal on programmed cell death

Avec: José Saura-Esteller , Ismael Sánchez-Vera , Sonia Núñez-Vázquez , Judith Jabalquinto-Carrasco , Ana M Cosialls , Lorena Mendive-Tapia , Dmytro Kukhtar , Manuel D Martínez-Bueno , Rodolfo Lavilla , Julián Cerón , Marta Artal-Sanz , Gabriel Pons , Daniel Iglesias-Serret , Joan Gil

New Trimethoprim-Like Molecules: Bacteriological Evaluation and Insights into Their Action.

Antibiotics (Basel, Switzerland)

Avec: Marta Jorba , Marina Pedrola , Ouldouz Ghashghaei , Rocío Herráez , Lluis Campos-Vicens , Franciso Javier Luque , Rodolfo Lavilla , Miguel Viñas

The prohibitin-binding compound fluorizoline induces the pro-inflammatory cytokines interleukin-8 and interleukin-6 through the activation of JNK and p38 MAP kinases.

Biochemical pharmacology

Avec: Ismael Sánchez-Vera , José Saura-Esteller , Sonia Núñez-Vázquez , Ana M Cosialls , Ouldouz Ghashghaei , Rodolfo Lavilla , Gabriel Pons , Joan Gil , Daniel Iglesias-Serret

Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design.

Biomedicines

Avec: Pau Nadal Rodríguez , Ouldouz Ghashghaei , Andrea Bagán , Carmen Escolano , Rodolfo Lavilla

NOXA upregulation by the prohibitin-binding compound fluorizoline is transcriptionally regulated by integrated stress response-induced ATF3 and ATF4.

The FEBS journal

Avec: Sonia Núñez-Vázquez , Ismael Sánchez-Vera , José Saura-Esteller , Ana M Cosialls , Anaïs F M Noisier , Fernando Albericio , Rodolfo Lavilla , Gabriel Pons , Daniel Iglesias-Serret , Joan Gil

Extended Multicomponent Reactions with Indole Aldehydes: Access to Unprecedented Polyheterocyclic Scaffolds, Ligands of the Aryl Hydrocarbon Receptor.

Angewandte Chemie (International ed. in English)

Avec: Ouldouz Ghashghaei , Marina Pedrola , Francesca Seghetti , Victor V Martin , Ricardo Zavarce , Michal Babiak , Jiri Novacek , Frederick Hartung , Katharina M Rolfes , Thomas Haarmann-Stemmann , Rodolfo Lavilla

Fluorogenic Trp(redBODIPY) cyclopeptide targeting keratin 1 for imaging of aggressive carcinomas.

Chemical science

Avec: Ramon Subiros-Funosas , Vivian Cheuk Lam Ho , Nicole D Barth , Lorena Mendive-Tapia , Morena Pappalardo , Xavier Barril , Ruoyu Ma , Cheng-Bin Zhang , Bin-Zhi Qian , Miquel Sintes , Ouldouz Ghashghaei , Rodolfo Lavilla , Marc Vendrell

Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Avec: Pau Nadal Rodríguez , Ouldouz Ghashghaei , Anna M Schoepf , Sam Benson , Marc Vendrell , Rodolfo Lavilla

A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death.

Angewandte Chemie (Weinheim an der Bergstrasse, Germany)

Avec: Nicole D Barth , Lorena Mendive-Tapia , Ramon Subiros-Funosas , Ouldouz Ghashghaei , Rodolfo Lavilla , Laura Maiorino , Xue-Yan He , Ian Dransfield , Mikala Egeblad , Marc Vendrell

Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds.

Angewandte Chemie (International ed. in English)

Avec: Pau Nadal Rodríguez , Ouldouz Ghashghaei , Anna M Schoepf , Sam Benson , Marc Vendrell , Rodolfo Lavilla

Drugs from drugs: New chemical insights into a mature concept.

Drug discovery today

Avec: Eloy Lozano Baró , Federica Catti , Carolina Estarellas , Ouldouz Ghashghaei , Rodolfo Lavilla

Réseau de co-auteurs

Ouldouz Ghashghaei 15 collaborations

Marc Vendrell 8 collaborations

Lorena Mendive-Tapia 7 collaborations

José Saura-Esteller 6 collaborations

Ismael Sánchez-Vera 6 collaborations

Sonia Núñez-Vázquez 6 collaborations

Ana M Cosialls 6 collaborations

Gabriel Pons 6 collaborations

Daniel Iglesias-Serret 6 collaborations

Joan Gil 6 collaborations

Marina Pedrola 4 collaborations

Nicole D Barth 4 collaborations

Ramon Subiros-Funosas 4 collaborations

Pau Nadal Rodríguez 4 collaborations

Miguel Viñas 3 collaborations

Ian Dransfield 3 collaborations

Mikala Egeblad 3 collaborations

Anna M Schoepf 3 collaborations

Marta Jorba 2 collaborations

Laura Maiorino 2 collaborations

Xue-Yan He 2 collaborations

Miquel Sintes 2 collaborations

Francesca Seghetti 2 collaborations

Sam Benson 2 collaborations

Eda Jardas 1 collaboration

Ferran Jardi 1 collaboration

Pau Gama-Pérez 1 collaboration

Gauri Bhosale 1 collaboration

Pablo M Garcia-Roves 1 collaboration

Michael R Duchen 1 collaboration

Antonio Fernandez 1 collaboration

Nicola Kielland 1 collaboration

Ashraff Makda 1 collaboration

Neil O Carragher 1 collaboration

M Carmen González-García 1 collaboration

Laura Espinar-Barranco 1 collaboration

Juan A González-Vera 1 collaboration

Angel Orte 1 collaboration

Marco Bertolini 1 collaboration

Abigail Reese 1 collaboration

Charles Lochenie 1 collaboration

Karolina Tokarczyk 1 collaboration

Zandile Nare 1 collaboration

Andrew D Scott 1 collaboration

Stephen R Knight 1 collaboration

Advait R Aithal 1 collaboration

Amit Sachdeva 1 collaboration

Angela Trejo 1 collaboration

Carme Masdeu 1 collaboration

Irene Serrano-Pérez 1 collaboration

Narcís Juanola 1 collaboration

Guadalupe Jiménez-Galisteo 1 collaboration

Francisco Palacios 1 collaboration

Concepción Alonso 1 collaboration

Judith Heib 1 collaboration

Helena Pomares 1 collaboration

Judit Perramon-Andújar 1 collaboration

Sandra Sanchez-Esteban 1 collaboration

Claudia M Palmeri 1 collaboration

Eva M González-Barca 1 collaboration

Rodger Duffin 1 collaboration

Mario A Shields 1 collaboration

Jennifer A Cartwright 1 collaboration

Sónia Troeira Henriques 1 collaboration

Jesus Sot 1 collaboration

Felix M Goñi 1 collaboration

John A Marwick 1 collaboration

Sonja Vermeren 1 collaboration

Adriano G Rossi 1 collaboration

Judith Jabalquinto-Carrasco 1 collaboration

Dmytro Kukhtar 1 collaboration

Manuel D Martínez-Bueno 1 collaboration

Julián Cerón 1 collaboration

Marta Artal-Sanz 1 collaboration

Rocío Herráez 1 collaboration

Lluis Campos-Vicens 1 collaboration

Franciso Javier Luque 1 collaboration

Andrea Bagán 1 collaboration

Carmen Escolano 1 collaboration

Anaïs F M Noisier 1 collaboration

Fernando Albericio 1 collaboration

Victor V Martin 1 collaboration

Ricardo Zavarce 1 collaboration

Michal Babiak 1 collaboration

Jiri Novacek 1 collaboration

Frederick Hartung 1 collaboration

Katharina M Rolfes 1 collaboration

Thomas Haarmann-Stemmann 1 collaboration

Vivian Cheuk Lam Ho 1 collaboration

Morena Pappalardo 1 collaboration

Xavier Barril 1 collaboration

Ruoyu Ma 1 collaboration

Cheng-Bin Zhang 1 collaboration

Bin-Zhi Qian 1 collaboration

Eloy Lozano Baró 1 collaboration

Federica Catti 1 collaboration

Carolina Estarellas 1 collaboration