Mutations involved in the emergence of Yersinia ruckeri biotype 2 in France.


Journal

Transboundary and emerging diseases
ISSN: 1865-1682
Titre abrégé: Transbound Emerg Dis
Pays: Germany
ID NLM: 101319538

Informations de publication

Date de publication:
May 2019
Historique:
received: 22 01 2019
revised: 05 03 2019
accepted: 10 03 2019
pubmed: 16 3 2019
medline: 31 8 2019
entrez: 16 3 2019
Statut: ppublish

Résumé

Yersina ruckeri is an enterobacteria responsible for Enteric redmouth disease (ERM), which causes significant economic losses in the aquaculture industry worldwide. Two biotypes have been described within Y. ruckeri: biotype 1 (BT1) and biotype 2 (BT2). Unlike BT1, BT2 is negative for motility and lipase secretion. The emergence of BT2 Y. ruckeri has been associated with disease outbreaks in vaccinated fish in several countries, notably France in the early 2000s. In this study, 15 BT2 strains (14 BT2 strains isolated in France and the BT2 reference strain EX5) were studied to compare the phenotypic characters of the BT1 and BT2 strains and to determine the genetic origin of the emergence of BT2 in France. BT1 bacteria are significantly longer in size than BT2 bacteria (a difference of 0.222 µm). The loss of motility of some French BT2 strains could be due to the loss of their ability to produce flagella caused by three mutations within the fliG, flhC and flgA genes. In the light of these results, the emergence of BT2 Yersinia ruckeri in France is discussed.

Identifiants

pubmed: 30874374
doi: 10.1111/tbed.13175
doi:

Substances chimiques

Bacterial Proteins 0
Flig protein, Bacteria 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1387-1394

Informations de copyright

© 2019 Blackwell Verlag GmbH.

Auteurs

Tatiana Thomas (T)

BIOEPAR, INRA, Nantes, France.
Université de Bretagne-Sud, IRDL, CNRS FRE 3744, Lorient, France.

Marie Brevet (M)

BIOEPAR, INRA, Nantes, France.

Chantal Thorin (C)

Department of Animal Physiopathology and Pharmacology, Oniris, Nantes, France.

Catherine Fournel (C)

BIOEPAR, INRA, Nantes, France.

Ségolène Calvez (S)

BIOEPAR, INRA, Nantes, France.

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Classifications MeSH