Patient and disease characteristics of type-2 diabetes patients with or without chronic kidney disease: an analysis of the German DPV and DIVE databases.
Age Factors
Aged
Albuminuria
/ diagnosis
Angiotensin Receptor Antagonists
/ therapeutic use
Angiotensin-Converting Enzyme Inhibitors
/ therapeutic use
Austria
/ epidemiology
Comorbidity
Databases, Factual
Diabetes Mellitus, Type 2
/ diagnosis
Diabetic Nephropathies
/ diagnosis
Diuretics
/ therapeutic use
Female
Germany
/ epidemiology
Glomerular Filtration Rate
Humans
Hypoglycemic Agents
/ therapeutic use
Kidney
/ physiopathology
Luxembourg
/ epidemiology
Male
Middle Aged
Prevalence
Registries
Renal Insufficiency, Chronic
/ diagnosis
Risk Assessment
Risk Factors
Sex Factors
Chronic kidney disease
DIVE
DPV
Disease characteristics
Patient characteristics
Type-2-diabetes
Journal
Cardiovascular diabetology
ISSN: 1475-2840
Titre abrégé: Cardiovasc Diabetol
Pays: England
ID NLM: 101147637
Informations de publication
Date de publication:
16 03 2019
16 03 2019
Historique:
received:
22
01
2019
accepted:
01
03
2019
entrez:
18
3
2019
pubmed:
18
3
2019
medline:
24
4
2019
Statut:
epublish
Résumé
To evaluate the characteristics of type 2 diabetes (T2DM) patients with or without chronic kidney disease (CKD) in Germany. Using combined DPV/DIVE registry data, the analysis included patients with T2DM at least ≥ 18 years old who had an estimated glomerular filtration rate (eGFR) value available. CKD was defined as an eGFR < 60 mL/min/1.73 m Among 343,675 patients with T2DM 171,930 had CKD. Patients with CKD had a median eGFR of 48.9 mL/min/1.73 m The results illustrate the prevalence and morbidity burden associated with diabetic kidney disease in patients with T2DM in Germany. The data call for more attention to the presence of chronic kidney disease in patients with diabetes, should trigger intensified risk factor control up and beyond the control of blood glucose and HbA1c in these patients. They may also serve as a trigger for future investigations into this patient population asking for new treatment options to be developed.
Sections du résumé
BACKGROUND
To evaluate the characteristics of type 2 diabetes (T2DM) patients with or without chronic kidney disease (CKD) in Germany.
METHODS
Using combined DPV/DIVE registry data, the analysis included patients with T2DM at least ≥ 18 years old who had an estimated glomerular filtration rate (eGFR) value available. CKD was defined as an eGFR < 60 mL/min/1.73 m
RESULTS
Among 343,675 patients with T2DM 171,930 had CKD. Patients with CKD had a median eGFR of 48.9 mL/min/1.73 m
CONCLUSION
The results illustrate the prevalence and morbidity burden associated with diabetic kidney disease in patients with T2DM in Germany. The data call for more attention to the presence of chronic kidney disease in patients with diabetes, should trigger intensified risk factor control up and beyond the control of blood glucose and HbA1c in these patients. They may also serve as a trigger for future investigations into this patient population asking for new treatment options to be developed.
Identifiants
pubmed: 30878037
doi: 10.1186/s12933-019-0837-x
pii: 10.1186/s12933-019-0837-x
pmc: PMC6420726
doi:
Substances chimiques
Angiotensin Receptor Antagonists
0
Angiotensin-Converting Enzyme Inhibitors
0
Diuretics
0
Hypoglycemic Agents
0
Types de publication
Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
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