Diagnostic strategy with a solid pancreatic mass.
Abdominal Pain
/ etiology
Adenocarcinoma
/ diagnosis
Ampulla of Vater
/ pathology
Biomarkers, Tumor
/ analysis
Carcinoma, Acinar Cell
/ diagnosis
Diabetes Mellitus
/ etiology
Diagnosis, Differential
Diagnostic Imaging
Drainage
Endoscopy, Digestive System
Glucose Intolerance
/ etiology
Humans
Jaundice
/ etiology
Laparoscopy
Nausea
/ etiology
Neoplasm Staging
/ methods
Neuroendocrine Tumors
/ diagnosis
Palliative Care
Pancreatectomy
Pancreatic Neoplasms
/ diagnosis
Pancreatitis
/ diagnosis
Patient Selection
Vomiting
/ etiology
Journal
Presse medicale (Paris, France : 1983)
ISSN: 2213-0276
Titre abrégé: Presse Med
Pays: France
ID NLM: 8302490
Informations de publication
Date de publication:
Mar 2019
Mar 2019
Historique:
received:
30
08
2018
accepted:
13
02
2019
pubmed:
18
3
2019
medline:
18
4
2019
entrez:
18
3
2019
Statut:
ppublish
Résumé
The correct diagnosis of a patient presenting with a solid pancreatic mass requires a careful diagnostic work-up, since many differential diagnoses are possible that completely alter the following treatments. In our chapter, we have discussed the clinical approach to the problem in a sort of diagnostic flow-chart. Firstly, we analysed the different potential presentations of a solid pancreatic mass, which can be both asymptomatic or symptomatic, and the differential diagnosis based on the symptoms of presentation. Then we focused on the various imaging techniques commonly used in the diagnostic work-up, stressing on the different presentations according to the type of disease, and the operative procedures that can supplement this part. Lastly, we discussed the best diagnostic work up that should be followed to fully understand the characteristics of each disease, which is of paramount importance to choose the adequate treatment plan, with special attention to pancreatic adenocarcinoma and its many treatment strategies such as chemotherapy, surgery, or medical therapy. In patients presenting with a solid pancreatic mass it is crucial to reach a definitive diagnosis using a well determined diagnostic work-up to better characterize the lesion, since the best treatment varies widely according not only to the type of disease but also to its features.
Identifiants
pubmed: 30878333
pii: S0755-4982(19)30075-2
doi: 10.1016/j.lpm.2019.02.026
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e125-e145Informations de copyright
Copyright © 2019 Elsevier Masson SAS. All rights reserved.