Diagnostic strategy with a solid pancreatic mass.


Journal

Presse medicale (Paris, France : 1983)
ISSN: 2213-0276
Titre abrégé: Presse Med
Pays: France
ID NLM: 8302490

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 30 08 2018
accepted: 13 02 2019
pubmed: 18 3 2019
medline: 18 4 2019
entrez: 18 3 2019
Statut: ppublish

Résumé

The correct diagnosis of a patient presenting with a solid pancreatic mass requires a careful diagnostic work-up, since many differential diagnoses are possible that completely alter the following treatments. In our chapter, we have discussed the clinical approach to the problem in a sort of diagnostic flow-chart. Firstly, we analysed the different potential presentations of a solid pancreatic mass, which can be both asymptomatic or symptomatic, and the differential diagnosis based on the symptoms of presentation. Then we focused on the various imaging techniques commonly used in the diagnostic work-up, stressing on the different presentations according to the type of disease, and the operative procedures that can supplement this part. Lastly, we discussed the best diagnostic work up that should be followed to fully understand the characteristics of each disease, which is of paramount importance to choose the adequate treatment plan, with special attention to pancreatic adenocarcinoma and its many treatment strategies such as chemotherapy, surgery, or medical therapy. In patients presenting with a solid pancreatic mass it is crucial to reach a definitive diagnosis using a well determined diagnostic work-up to better characterize the lesion, since the best treatment varies widely according not only to the type of disease but also to its features.

Identifiants

pubmed: 30878333
pii: S0755-4982(19)30075-2
doi: 10.1016/j.lpm.2019.02.026
pii:
doi:

Substances chimiques

Biomarkers, Tumor 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

e125-e145

Informations de copyright

Copyright © 2019 Elsevier Masson SAS. All rights reserved.

Auteurs

Giovanni Guarneri (G)

Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.

Giulia Gasparini (G)

Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.

Stefano Crippa (S)

Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy; "Vita-Salute" University, San Raffaele Scientific Institute, Milan, Italy.

Valentina Andreasi (V)

Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy.

Massimo Falconi (M)

Pancreas Translational & Clinical Research Center, San Raffaele Scientific Institute, Milan, Italy; "Vita-Salute" University, San Raffaele Scientific Institute, Milan, Italy. Electronic address: falconi.massimo@hsr.it.

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Classifications MeSH