Levetiracetam versus carbamazepine in treatment of rolandic epilepsy.
Antiepileptic
EEG
Levetiracetam
Rolandic
Treatment
Journal
Epilepsy & behavior : E&B
ISSN: 1525-5069
Titre abrégé: Epilepsy Behav
Pays: United States
ID NLM: 100892858
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
01
02
2019
revised:
08
02
2019
accepted:
08
02
2019
pubmed:
19
3
2019
medline:
1
7
2020
entrez:
19
3
2019
Statut:
ppublish
Résumé
The aim of the current study was to systematically review the literature to compare the efficacy of levetiracetam (LEV) with that of carbamazepine (CBZ) to control seizures and reduce the burden of interictal epileptiform discharges in children with rolandic epilepsy (RE) and also to compare their tolerability. We searched the electronic database PubMed on January 9, 2019 for original articles that included the following English-language search terms in the title: "Rolandic epilepsy" OR "benign childhood epilepsy with centrotemporal spikes" since 2000. We concentrated our review on three main areas: 1. Neuropsychological impairments in children with RE; 2. Influence of epileptic activity on cognitive performance in RE; 3. Effects of antiepileptic drug (AED) therapies in RE. The primary search yielded 308 papers. We reviewed the results and removed duplicate articles and all nonoriginal, non-English papers. Finally, after carefully reviewing the full texts, we included 44 original articles to achieve the aims of this review. Physicians taking care of children with RE should be aware of the risks for cognitive dysfunctions in these patients and screen their patients for any subtle dysfunction that may affect their academic performance and achievement. If and when the physician decides to prescribe an AED for their patients with RE, LEV is probably a better option compared with CBZ to prescribe for these children.
Identifiants
pubmed: 30884401
pii: S1525-5050(19)30114-3
doi: 10.1016/j.yebeh.2019.02.009
pii:
doi:
Substances chimiques
Anticonvulsants
0
Benzodiazepines
12794-10-4
Carbamazepine
33CM23913M
Levetiracetam
44YRR34555
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1-8Informations de copyright
Copyright © 2019 Elsevier Inc. All rights reserved.