Effects of Time to Application of Negative Pressure Therapy on Abdominal Infections After Colonic Perforation.


Journal

Surgical technology international
ISSN: 1090-3941
Titre abrégé: Surg Technol Int
Pays: United States
ID NLM: 9604509

Informations de publication

Date de publication:
15 May 2019
Historique:
pubmed: 20 3 2019
medline: 4 9 2019
entrez: 20 3 2019
Statut: ppublish

Résumé

Negative pressure therapy (NPT) seems to improve surgical outcomes in open abdomen (OA) management of severe intra-abdominal infections (IAIs). The aim of this study was to compare the effects of immediate vs. delayed application of NPT on outcomes in patients with IAIs after colonic perforation. We analysed 38 patients who received NPT during OA management for IAI after colonic perforation. The endpoints were treatment duration, definitive fascial closure and in-hospital mortality. We subdivided patients according to the timing of NPT application: immediate (at the end of the first OA procedure) and delayed (at I-II revision, at III revision, and after III revision). NPT was applied immediately in 15 cases (39.5%) and was delayed in 23 (60.5%): 14 (36.8%) at I-II revision, 7 (18.4%) at III revision, and 2 (5.3%) after III revision. Immediate NPT application was associated with the best outcomes. NPT should be used as soon as possible in OA management for IAIs due to colonic perforation.

Sections du résumé

BACKGROUND BACKGROUND
Negative pressure therapy (NPT) seems to improve surgical outcomes in open abdomen (OA) management of severe intra-abdominal infections (IAIs). The aim of this study was to compare the effects of immediate vs. delayed application of NPT on outcomes in patients with IAIs after colonic perforation.
MATERIALS AND METHODS METHODS
We analysed 38 patients who received NPT during OA management for IAI after colonic perforation. The endpoints were treatment duration, definitive fascial closure and in-hospital mortality. We subdivided patients according to the timing of NPT application: immediate (at the end of the first OA procedure) and delayed (at I-II revision, at III revision, and after III revision).
RESULTS RESULTS
NPT was applied immediately in 15 cases (39.5%) and was delayed in 23 (60.5%): 14 (36.8%) at I-II revision, 7 (18.4%) at III revision, and 2 (5.3%) after III revision. Immediate NPT application was associated with the best outcomes.
CONCLUSIONS CONCLUSIONS
NPT should be used as soon as possible in OA management for IAIs due to colonic perforation.

Identifiants

pubmed: 30888675
pii: sti34/1120

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

115-119

Auteurs

Stefano Rausei (S)

Department of Surgery, ASST Valle Olona Gallarate, Italy.

Vincenzo Pappalardo (V)

Department of Surgery, ASST Settelaghi, Varese, Italy.

Federica Galli (F)

Department of Surgery, ASST Settelaghi, Varese, Italy.

Simone Giudici (S)

Department of Surgery, ASST Settelaghi, Varese, Italy.

Antonio Colella (A)

Department of Surgery, ASST Settelaghi, Varese, Italy.

Rancesco Frattini (R)

Department of Surgery, ASST Settelaghi, Varese, Italy.

Luigi Boni (L)

Department of Surgery, IRCCS Ca' Granda - Policlinico Hospital, University of Milan, Milan, Italy.

Gianlorenzo Dionigi (G)

Department of Human Pathology, in Adulthood and Childhood, University of Messina, Messina, Italy.

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