Droplet Digital PCR Detection of the Erythropoietin Transgene from Horse Plasma and Urine for Gene-Doping Control.
disease mechanisms
domestic horse
equine genetics
exercise traits
genome-to-phenome
morphologic traits
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
21 03 2019
21 03 2019
Historique:
received:
20
02
2019
revised:
16
03
2019
accepted:
16
03
2019
entrez:
24
3
2019
pubmed:
25
3
2019
medline:
25
3
2019
Statut:
epublish
Résumé
Indiscriminate genetic manipulation to improve athletic ability is a major threat to human sports and the horseracing industry, in which methods involving gene-doping, such as transgenesis, should be prohibited to ensure fairness. Therefore, development of methods to detect indiscriminate genetic manipulation are urgently needed. Here, we developed a highly sensitive method to detect horse erythropoietin (
Identifiants
pubmed: 30901981
pii: genes10030243
doi: 10.3390/genes10030243
pmc: PMC6471249
pii:
doi:
Substances chimiques
Erythropoietin
11096-26-7
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Déclaration de conflit d'intérêts
There are no competing interests including patents, products in development, or marketed products to declare in relationship to this work.
Références
J Chromatogr A. 2012 Apr 6;1232:257-65
pubmed: 22265177
J Orthop Res. 2008 Jun;26(6):764-71
pubmed: 18241059
Mol Cell Probes. 2012 Dec;26(6):256-8
pubmed: 22433981
BMC Res Notes. 2018 Oct 29;11(1):770
pubmed: 30373660
Anal Chim Acta. 2011 Aug 26;700(1-2):126-36
pubmed: 21742125
Anal Bioanal Chem. 2013 Dec;405(30):9641-53
pubmed: 23912835
J Vet Med Sci. 2001 Nov;63(11):1191-7
pubmed: 11767052
Biomed Chromatogr. 2002 Dec;16(8):513-6
pubmed: 12474214
Front Vet Sci. 2017 Oct 10;4:168
pubmed: 29067288
Vet J. 2014 Apr;200(1):8-16
pubmed: 24485918
BMC Res Notes. 2018 Oct 10;11(1):708
pubmed: 30309394
Biomol Detect Quantif. 2014 Aug 15;1(1):1-2
pubmed: 27920991
Curr Gene Ther. 2011 Dec;11(6):447-56
pubmed: 22023474
J Nanosci Nanotechnol. 2019 Apr 1;19(4):1959-1970
pubmed: 30486936
Curr Gene Ther. 2014;14(2):86-100
pubmed: 24588706
Methods Mol Biol. 2011;764:1-15
pubmed: 21748630
Drug Test Anal. 2017 Sep;9(9):1456-1471
pubmed: 28349656