Extra-axial chordoma of the gingiva.
Bone tumour
Brachyury
Extra-axial chordoma
Surgical resection
Three-dimensional model
Journal
Auris, nasus, larynx
ISSN: 1879-1476
Titre abrégé: Auris Nasus Larynx
Pays: Netherlands
ID NLM: 7708170
Informations de publication
Date de publication:
Apr 2020
Apr 2020
Historique:
received:
16
11
2018
accepted:
08
03
2019
pubmed:
25
3
2019
medline:
23
3
2021
entrez:
25
3
2019
Statut:
ppublish
Résumé
Extra-axial chordomas are exceedingly rare malignant tumours. Herein, we present the first case of an extra-axial chordoma in the gingivae. A 21-year-old man presented with a suspected chordoma in the upper right gingiva. Diagnosis was difficult; however, owing to strong expression of the chordoma marker brachyury, extra-axial chordoma was ultimately diagnosed. The tumour was completely resected without performing a facial incision. To ensure its safety and effectiveness, the surgical procedure was simulated several times before its performance using a three-dimensional (3D) model. Twenty-four months after surgery, the patient remains disease-free. A diagnosis of extra-axial chordoma can be confirmed by immunohistochemical staining for brachyury.
Sections du résumé
BACKGROUND
BACKGROUND
Extra-axial chordomas are exceedingly rare malignant tumours. Herein, we present the first case of an extra-axial chordoma in the gingivae.
METHODS AND RESULTS
RESULTS
A 21-year-old man presented with a suspected chordoma in the upper right gingiva. Diagnosis was difficult; however, owing to strong expression of the chordoma marker brachyury, extra-axial chordoma was ultimately diagnosed. The tumour was completely resected without performing a facial incision. To ensure its safety and effectiveness, the surgical procedure was simulated several times before its performance using a three-dimensional (3D) model. Twenty-four months after surgery, the patient remains disease-free.
CONCLUSION
CONCLUSIONS
A diagnosis of extra-axial chordoma can be confirmed by immunohistochemical staining for brachyury.
Identifiants
pubmed: 30904199
pii: S0385-8146(18)30973-8
doi: 10.1016/j.anl.2019.03.005
pii:
doi:
Substances chimiques
Fetal Proteins
0
T-Box Domain Proteins
0
Brachyury protein
EQ43SC3GDB
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
299-304Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.