Translocator protein localises to CD11b
Journal
Atherosclerosis
ISSN: 1879-1484
Titre abrégé: Atherosclerosis
Pays: Ireland
ID NLM: 0242543
Informations de publication
Date de publication:
05 2019
05 2019
Historique:
received:
07
01
2019
revised:
12
03
2019
accepted:
14
03
2019
pubmed:
27
3
2019
medline:
4
6
2020
entrez:
27
3
2019
Statut:
ppublish
Résumé
Atherosclerosis is characterized by lipid deposition, monocyte infiltration and foam cell formation in the artery wall. Translocator protein (TSPO) is abundantly expressed in lipid rich tissues. Recently, TSPO has been identified as a potential diagnostic tool in cardiovascular disease. The purpose of this study was to determine if the TSPO ligand, ApoE While tissue resident F4/80 Imaging of TSPO expression is a new approach for studying atherosclerotic lesion progression and inflammatory cell infiltration. The TSPO ligand,
Sections du résumé
BACKGROUND AND AIMS
Atherosclerosis is characterized by lipid deposition, monocyte infiltration and foam cell formation in the artery wall. Translocator protein (TSPO) is abundantly expressed in lipid rich tissues. Recently, TSPO has been identified as a potential diagnostic tool in cardiovascular disease. The purpose of this study was to determine if the TSPO ligand,
METHODS
ApoE
RESULTS
While tissue resident F4/80
CONCLUSIONS
Imaging of TSPO expression is a new approach for studying atherosclerotic lesion progression and inflammatory cell infiltration. The TSPO ligand,
Identifiants
pubmed: 30913515
pii: S0021-9150(19)30140-6
doi: 10.1016/j.atherosclerosis.2019.03.011
pii:
doi:
Substances chimiques
2-(6-chloro-2-(4-(3-fluoropropoxy)phenyl)imidazo(1,2-a)pyridin-3-yl)-N,N-diethylacetamide
0
Bzrp protein, mouse
0
CD11b Antigen
0
Itgam protein, mouse
0
Pyridines
0
Receptors, GABA
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
153-159Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.