Assessment of histotripsy-induced liquefaction with diagnostic ultrasound and magnetic resonance imaging in vitro and ex vivo.
Journal
Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220
Informations de publication
Date de publication:
02 05 2019
02 05 2019
Historique:
pubmed:
29
3
2019
medline:
26
2
2020
entrez:
29
3
2019
Statut:
epublish
Résumé
Histotripsy is a therapeutic ultrasound modality under development to liquefy tissue mechanically via bubble clouds. Image guidance of histotripsy requires both quantification of the bubble cloud activity and accurate delineation of the treatment zone. In this study, magnetic resonance (MR) and diagnostic ultrasound imaging were combined to assess histotripsy treatment in vitro and ex vivo. Mechanically ablative histotripsy pulses were applied to agarose phantoms or porcine livers. Bubble cloud emissions were monitored with passive cavitation imaging (PCI), and hyperechogenicity via plane wave imaging. Changes in the medium structure due to bubble activity were assessed with diagnostic ultrasound using conventional B-mode imaging and T
Identifiants
pubmed: 30921780
doi: 10.1088/1361-6560/ab143f
pmc: PMC6706274
mid: NIHMS1045279
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
095023Subventions
Organisme : NCI NIH HHS
ID : K12 CA139160
Pays : United States
Organisme : NCI NIH HHS
ID : P30 CA014599
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL133334
Pays : United States
Organisme : NIBIB NIH HHS
ID : T32 EB002103
Pays : United States
Commentaires et corrections
Type : ErratumIn
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