Nutrient and Stress Sensing in Pathogenic Yeasts.
G protein-coupled receptor
Mep2
Tor
fungal pathogen
nutrient sensing
stress response
transceptor
yeast
Journal
Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977
Informations de publication
Date de publication:
2019
2019
Historique:
received:
09
01
2019
accepted:
20
02
2019
entrez:
2
4
2019
pubmed:
2
4
2019
medline:
2
4
2019
Statut:
epublish
Résumé
More than 1.5 million fungal species are estimated to live in vastly different environmental niches. Despite each unique host environment, fungal cells sense certain fundamentally conserved elements, such as nutrients, pheromones and stress, for adaptation to their niches. Sensing these extracellular signals is critical for pathogens to adapt to the hostile host environment and cause disease. Hence, dissecting the complex extracellular signal-sensing mechanisms that aid in this is pivotal and may facilitate the development of new therapeutic approaches to control fungal infections. In this review, we summarize the current knowledge on how two important pathogenic yeasts,
Identifiants
pubmed: 30930866
doi: 10.3389/fmicb.2019.00442
pmc: PMC6423903
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
442Subventions
Organisme : NIAID NIH HHS
ID : R01 AI050113
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI123315
Pays : United States
Organisme : NIAID NIH HHS
ID : R37 AI039115
Pays : United States
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