Joseph Heitman

Affiliations

Department of Molecular Genetics and Microbiology, Duke University Medical Centre, Durham, NC, USA.

Publications (31)

Advances in understanding the evolution of fungal genome architecture.

F1000Research

Avec: Shelby J Priest , Vikas Yadav , Joseph Heitman

Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture.

mBio

Avec: Matthew C Fisher , Sarah J Gurr , Christina A Cuomo , David S Blehert , Hailing Jin , Eva H Stukenbrock , Jason E Stajich , Regine Kahmann , Charles Boone , David W Denning , Neil A R Gow , Bruce S Klein , James W Kronstad , Donald C Sheppard , John W Taylor , Gerard D Wright , Joseph Heitman , Arturo Casadevall , Leah E Cowen

mBio

Avec: Shelly Applen Clancey , Emily J Ciccone , Marco A Coelho , Joie Davis , Li Ding , Renee Betancourt , Samuel Glaubiger , Yueh Lee , Steven M Holland , Peter Gilligan , Julia Sung , Joseph Heitman

Fungi in the Marine Environment: Open Questions and Unsolved Problems.

mBio

Avec: Anthony Amend , Gaetan Burgaud , Michael Cunliffe , Virginia P Edgcomb , Cassandra L Ettinger , M H Gutiérrez , Joseph Heitman , Erik F Y Hom , Giuseppe Ianiri , Adam C Jones , Maiko Kagami , Kathryn T Picard , C Alisha Quandt , Seshagiri Raghukumar , Mertixell Riquelme , Jason Stajich , José Vargas-Muñiz , Allison K Walker , Oded Yarden , Amy S Gladfelter

Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides.

PLoS genetics

Avec: Zanetta Chang , R Blake Billmyre , Soo Chan Lee , Joseph Heitman

Gastrointestinal microbiota alteration induced by Mucor circinelloides in a murine model.

Journal of microbiology (Seoul, Korea)

Avec: Katherine D Mueller , Hao Zhang , Christian R Serrano , R Blake Billmyre , Eun Young Huh , Philipp Wiemann , Nancy P Keller , Yufeng Wang , Joseph Heitman , Soo Chan Lee

Clonal evolution in serially passaged Cryptococcus neoformans × deneoformans hybrids reveals a heterogenous landscape of genomic change.

Genetics

Avec: Lucas A Michelotti , Sheng Sun , Joseph Heitman , Timothy Y James

On the evolution of variation in sexual reproduction through the prism of eukaryotic microbes.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Vikas Yadav , Sheng Sun , Joseph Heitman

Frequent transitions in mating-type locus chromosomal organization in

bioRxiv : the preprint server for biology

Avec: Marco A Coelho , Giuseppe Ianiri , Márcia David-Palma , Bart Theelen , Rohit Goyal , Aswathy Narayanan , Jeffrey M Lorch , Kaustuv Sanyal , Teun Boekhout , Joseph Heitman

Lessons learned: from mentored to mentor.

The Journal of clinical investigation

Avec: Joseph Heitman

Calcineurin contributes to RNAi-mediated transgene silencing and small interfering RNA production in the human fungal pathogen Cryptococcus neoformans.

Genetics

Avec: Vikas Yadav , Riya Mohan , Sheng Sun , Joseph Heitman

Comparative genomics of

bioRxiv : the preprint server for biology

Avec: Marco A Coelho , Márcia David-Palma , Terrance Shea , Katharine Bowers , Sage McGinley-Smith , Arman W Mohammad , Andreas Gnirke , Andrey M Yurkov , Minou Nowrousian , Sheng Sun , Christina A Cuomo , Joseph Heitman

Epigenetic mechanisms of drug resistance in fungi.

Fungal genetics and biology : FG & B

Avec: Zanetta Chang , Vikas Yadav , Soo Chan Lee , Joseph Heitman

Early Diverging Fungus Mucor circinelloides Lacks Centromeric Histone CENP-A and Displays a Mosaic of Point and Regional Centromeres.

Current biology : CB

Avec: María Isabel Navarro-Mendoza , Carlos Pérez-Arques , Shweta Panchal , Francisco E Nicolás , Stephen J Mondo , Promit Ganguly , Jasmyn Pangilinan , Igor V Grigoriev , Joseph Heitman , Kaustuv Sanyal , Victoriano Garre

Nutrient and Stress Sensing in Pathogenic Yeasts.

Frontiers in microbiology

Avec: Julian C Rutherford , Yong-Sun Bahn , Bert van den Berg , Joseph Heitman , Chaoyang Xue

Genetic and Genomic Analyses Reveal Boundaries between Species Closely Related to

mBio

Avec: Andrew Ryan Passer , Marco A Coelho , Robert Blake Billmyre , Minou Nowrousian , Moritz Mittelbach , Andrey M Yurkov , Anna Floyd Averette , Christina A Cuomo , Sheng Sun , Joseph Heitman

5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus.

Nature communications

Avec: R Blake Billmyre , Shelly Applen Clancey , Lucy X Li , Tamara L Doering , Joseph Heitman

Centromere deletion in

eLife

Avec: Klaas Schotanus , Joseph Heitman

HGT in the human and skin commensal

Proceedings of the National Academy of Sciences of the United States of America

Avec: Giuseppe Ianiri , Marco A Coelho , Fiorella Ruchti , Florian Sparber , Timothy J McMahon , Ci Fu , Madison Bolejack , Olivia Donovan , Hayden Smutney , Peter Myler , Fred Dietrich , David Fox , Salomé LeibundGut-Landmann , Joseph Heitman

FKBP12 dimerization mutations effect FK506 binding and differentially alter calcineurin inhibition in the human pathogen Aspergillus fumigatus.

Biochemical and biophysical research communications

Avec: Praveen R Juvvadi , Benjamin G Bobay , Sophie M C Gobeil , D Christopher Cole , Ronald A Venters , Joseph Heitman , Leonard D Spicer , William J Steinbach

Long transposon-rich centromeres in an oomycete reveal divergence of centromere features in Stramenopila-Alveolata-Rhizaria lineages.

PLoS genetics

Avec: Yufeng Fang , Marco A Coelho , Haidong Shu , Klaas Schotanus , Bhagya C Thimmappa , Vikas Yadav , Han Chen , Ewa P Malc , Jeremy Wang , Piotr A Mieczkowski , Brent Kronmiller , Brett M Tyler , Kaustuv Sanyal , Suomeng Dong , Minou Nowrousian , Joseph Heitman

Dynamic genome plasticity during unisexual reproduction in the human fungal pathogen Cryptococcus deneoformans.

PLoS genetics

Avec: Ci Fu , Aaliyah Davy , Simeon Holmes , Sheng Sun , Vikas Yadav , Asiya Gusa , Marco A Coelho , Joseph Heitman

Joseph Heitman.

Current biology : CB

Avec: Joseph Heitman

Epistatic genetic interactions govern morphogenesis during sexual reproduction and infection in a global human fungal pathogen.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Sheng Sun , Cullen Roth , Anna Floyd Averette , Paul M Magwene , Joseph Heitman

Exploring Space via Astromycology: A Report on the CIFAR Programs

Astrobiology

Avec: Nicola T Case , Min Song , Avery H Fulford , Heather V Graham , Victoria J Orphan , Jason E Stajich , Arturo Casadevall , John Mustard , Joseph Heitman , Barbara Sherwood Lollar , Leah E Cowen

Frequent transitions in mating-type locus chromosomal organization in

Proceedings of the National Academy of Sciences of the United States of America

Avec: Marco A Coelho , Giuseppe Ianiri , Márcia David-Palma , Bart Theelen , Rohit Goyal , Aswathy Narayanan , Jeffrey M Lorch , Kaustuv Sanyal , Teun Boekhout , Joseph Heitman

The future of fungi: threats and opportunities.

G3 (Bethesda, Md.)

Avec: Nicola T Case , Judith Berman , David S Blehert , Robert A Cramer , Christina Cuomo , Cameron R Currie , Iuliana V Ene , Matthew C Fisher , Lillian K Fritz-Laylin , Aleeza C Gerstein , N Louise Glass , Neil A R Gow , Sarah J Gurr , Chris Todd Hittinger , Tobias M Hohl , Iliyan D Iliev , Timothy Y James , Hailing Jin , Bruce S Klein , James W Kronstad , Jeffrey M Lorch , Victoria McGovern , Aaron P Mitchell , Julia A Segre , Rebecca S Shapiro , Donald C Sheppard , Anita Sil , Jason E Stajich , Eva E Stukenbrock , John W Taylor , Dawn Thompson , Gerard D Wright , Joseph Heitman , Leah E Cowen

Enhanced fungal specificity and

bioRxiv : the preprint server for biology

Avec: Angela Rivera , Won Young Lim , Eunchong Park , Patrick A Dome , Michael J Hoy , Ivan Spasojevic , Sheng Sun , Anna Floyd Averette , Sergio Pina-Oviedo , Praveen R Juvvadi , William J Steinbach , Maria Ciofani , Jiyong Hong , Joseph Heitman

Amoeba predation of Cryptococcus: A quantitative and population genomic evaluation of the accidental pathogen hypothesis.

PLoS pathogens

Avec: Thomas J C Sauters , Cullen Roth , Debra Murray , Sheng Sun , Anna Floyd Averette , Chinaemerem U Onyishi , Robin C May , Joseph Heitman , Paul M Magwene

Tornadic Shear Stress Induces a Transient, Calcineurin-Dependent Hypervirulent Phenotype in Mucorales Molds.

mBio

Avec: Sebastian Wurster , Alexander M Tatara , Nathaniel D Albert , Ashraf S Ibrahim , Joseph Heitman , Soo Chan Lee , Amol C Shetty , Carrie McCracken , Karen T Graf , Antonios G Mikos , Vincent M Bruno , Dimitrios P Kontoyiannis

Expression of a

Frontiers in cellular and infection microbiology

Avec: Joleen P Z Goh , Giuseppe Ianiri , Joseph Heitman , Thomas L Dawson

Réseau de co-auteurs

Sheng Sun 9 collaborations

Marco A Coelho 8 collaborations

Vikas Yadav 6 collaborations

Giuseppe Ianiri 5 collaborations

Soo Chan Lee 4 collaborations

Kaustuv Sanyal 4 collaborations

Anna Floyd Averette 4 collaborations

Christina A Cuomo 3 collaborations

Jason E Stajich 3 collaborations

Leah E Cowen 3 collaborations

R Blake Billmyre 3 collaborations

Márcia David-Palma 3 collaborations

Jeffrey M Lorch 3 collaborations

Minou Nowrousian 3 collaborations

Matthew C Fisher 2 collaborations

Sarah J Gurr 2 collaborations

David S Blehert 2 collaborations

Hailing Jin 2 collaborations

Neil A R Gow 2 collaborations

Bruce S Klein 2 collaborations

James W Kronstad 2 collaborations

Donald C Sheppard 2 collaborations

John W Taylor 2 collaborations

Gerard D Wright 2 collaborations

Arturo Casadevall 2 collaborations

Shelly Applen Clancey 2 collaborations

Zanetta Chang 2 collaborations

Timothy Y James 2 collaborations

Bart Theelen 2 collaborations

Rohit Goyal 2 collaborations

Aswathy Narayanan 2 collaborations

Teun Boekhout 2 collaborations

Andrey M Yurkov 2 collaborations

Klaas Schotanus 2 collaborations

Ci Fu 2 collaborations

Praveen R Juvvadi 2 collaborations

William J Steinbach 2 collaborations

Cullen Roth 2 collaborations

Paul M Magwene 2 collaborations

Nicola T Case 2 collaborations

Shelby J Priest 1 collaboration

Eva H Stukenbrock 1 collaboration

Regine Kahmann 1 collaboration

Charles Boone 1 collaboration

David W Denning 1 collaboration

Emily J Ciccone 1 collaboration

Joie Davis 1 collaboration

Li Ding 1 collaboration

Renee Betancourt 1 collaboration

Samuel Glaubiger 1 collaboration

Yueh Lee 1 collaboration

Steven M Holland 1 collaboration

Peter Gilligan 1 collaboration

Julia Sung 1 collaboration

Anthony Amend 1 collaboration

Gaetan Burgaud 1 collaboration

Michael Cunliffe 1 collaboration

Virginia P Edgcomb 1 collaboration

Cassandra L Ettinger 1 collaboration

M H Gutiérrez 1 collaboration

Erik F Y Hom 1 collaboration

Adam C Jones 1 collaboration

Maiko Kagami 1 collaboration

Kathryn T Picard 1 collaboration

C Alisha Quandt 1 collaboration

Seshagiri Raghukumar 1 collaboration

Mertixell Riquelme 1 collaboration

Jason Stajich 1 collaboration

José Vargas-Muñiz 1 collaboration

Allison K Walker 1 collaboration

Oded Yarden 1 collaboration

Amy S Gladfelter 1 collaboration

Katherine D Mueller 1 collaboration

Hao Zhang 1 collaboration

Christian R Serrano 1 collaboration

Eun Young Huh 1 collaboration

Philipp Wiemann 1 collaboration

Nancy P Keller 1 collaboration

Yufeng Wang 1 collaboration

Lucas A Michelotti 1 collaboration

Riya Mohan 1 collaboration

Terrance Shea 1 collaboration

Katharine Bowers 1 collaboration

Sage McGinley-Smith 1 collaboration

Arman W Mohammad 1 collaboration

Andreas Gnirke 1 collaboration

María Isabel Navarro-Mendoza 1 collaboration

Carlos Pérez-Arques 1 collaboration

Shweta Panchal 1 collaboration

Francisco E Nicolás 1 collaboration

Stephen J Mondo 1 collaboration

Promit Ganguly 1 collaboration

Jasmyn Pangilinan 1 collaboration

Igor V Grigoriev 1 collaboration

Victoriano Garre 1 collaboration

Julian C Rutherford 1 collaboration

Yong-Sun Bahn 1 collaboration

Bert van den Berg 1 collaboration

Chaoyang Xue 1 collaboration

Andrew Ryan Passer 1 collaboration

Robert Blake Billmyre 1 collaboration

Moritz Mittelbach 1 collaboration

Lucy X Li 1 collaboration

Tamara L Doering 1 collaboration

Fiorella Ruchti 1 collaboration

Florian Sparber 1 collaboration

Timothy J McMahon 1 collaboration

Madison Bolejack 1 collaboration

Olivia Donovan 1 collaboration

Hayden Smutney 1 collaboration

Peter Myler 1 collaboration

Fred Dietrich 1 collaboration

David Fox 1 collaboration

Salomé LeibundGut-Landmann 1 collaboration

Benjamin G Bobay 1 collaboration

Sophie M C Gobeil 1 collaboration

D Christopher Cole 1 collaboration

Ronald A Venters 1 collaboration

Leonard D Spicer 1 collaboration

Yufeng Fang 1 collaboration

Haidong Shu 1 collaboration

Bhagya C Thimmappa 1 collaboration

Han Chen 1 collaboration

Ewa P Malc 1 collaboration

Jeremy Wang 1 collaboration

Piotr A Mieczkowski 1 collaboration

Brent Kronmiller 1 collaboration

Brett M Tyler 1 collaboration

Suomeng Dong 1 collaboration

Aaliyah Davy 1 collaboration

Simeon Holmes 1 collaboration

Asiya Gusa 1 collaboration

Min Song 1 collaboration

Avery H Fulford 1 collaboration

Heather V Graham 1 collaboration

Victoria J Orphan 1 collaboration

John Mustard 1 collaboration

Barbara Sherwood Lollar 1 collaboration

Judith Berman 1 collaboration

Robert A Cramer 1 collaboration

Christina Cuomo 1 collaboration

Cameron R Currie 1 collaboration

Iuliana V Ene 1 collaboration

Lillian K Fritz-Laylin 1 collaboration

Aleeza C Gerstein 1 collaboration

N Louise Glass 1 collaboration

Chris Todd Hittinger 1 collaboration

Tobias M Hohl 1 collaboration

Iliyan D Iliev 1 collaboration

Victoria McGovern 1 collaboration

Aaron P Mitchell 1 collaboration

Julia A Segre 1 collaboration

Rebecca S Shapiro 1 collaboration

Anita Sil 1 collaboration

Eva E Stukenbrock 1 collaboration

Dawn Thompson 1 collaboration

Angela Rivera 1 collaboration

Won Young Lim 1 collaboration

Eunchong Park 1 collaboration

Patrick A Dome 1 collaboration

Michael J Hoy 1 collaboration

Ivan Spasojevic 1 collaboration

Sergio Pina-Oviedo 1 collaboration

Maria Ciofani 1 collaboration

Jiyong Hong 1 collaboration

Thomas J C Sauters 1 collaboration

Debra Murray 1 collaboration

Chinaemerem U Onyishi 1 collaboration

Robin C May 1 collaboration

Sebastian Wurster 1 collaboration

Alexander M Tatara 1 collaboration

Nathaniel D Albert 1 collaboration

Ashraf S Ibrahim 1 collaboration

Amol C Shetty 1 collaboration

Carrie McCracken 1 collaboration

Karen T Graf 1 collaboration

Antonios G Mikos 1 collaboration

Vincent M Bruno 1 collaboration

Dimitrios P Kontoyiannis 1 collaboration

Joleen P Z Goh 1 collaboration

Thomas L Dawson 1 collaboration