Chondrocyte Culture Parameters for Matrix-Assisted Autologous Chondrocyte Implantation Affect Catabolism and Inflammation in a Rabbit Model.
animal model
cell density
cell passage
cytokines
matrix metalloproteinases
matrix-assisted autologous chondrocyte implantation
membrane-holding time
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
27 Mar 2019
27 Mar 2019
Historique:
received:
16
02
2019
revised:
22
03
2019
accepted:
25
03
2019
entrez:
3
4
2019
pubmed:
3
4
2019
medline:
17
7
2019
Statut:
epublish
Résumé
Cartilage defects represent an increasing pathology among active individuals that affects the ability to contribute to sports and daily life. Cell therapy, such as autologous chondrocyte implantation (ACI), is a widespread option to treat larger cartilage defects still lacking standardization of in vitro cell culture parameters. We hypothesize that mRNA expression of cytokines and proteases before and after ACI is influenced by in vitro parameters: cell-passage, cell-density and membrane-holding time. Knee joint articular chondrocytes, harvested from rabbits (
Identifiants
pubmed: 30934789
pii: ijms20071545
doi: 10.3390/ijms20071545
pmc: PMC6479589
pii:
doi:
Substances chimiques
Cytokines
0
Inflammation Mediators
0
RNA, Messenger
0
Matrix Metalloproteinases
EC 3.4.24.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Gesellschaft für Arthroskopie und Gelenkchirurgie (AGA)
ID : 26/2007
Références
Methods Mol Biol. 2000;132:365-86
pubmed: 10547847
Biomaterials. 2000 Mar;21(6):571-80
pubmed: 10701458
Arthritis Rheum. 2001 Mar;44(3):585-94
pubmed: 11263773
Methods. 2001 Dec;25(4):402-8
pubmed: 11846609
J Orthop Res. 2003 Mar;21(2):272-81
pubmed: 12568959
Arthroscopy. 2003 Apr;19(4):397-403
pubmed: 12671623
Clin Orthop Relat Res. 2004 Oct;(427 Suppl):S27-36
pubmed: 15480070
Ann Rheum Dis. 2005 Sep;64(9):1263-7
pubmed: 15731292
J Orthop Res. 2005 Mar;23(2):425-32
pubmed: 15734258
Tissue Eng. 2005 Jul-Aug;11(7-8):1065-76
pubmed: 16144442
Eur J Radiol. 2006 Jan;57(1):24-31
pubmed: 16188417
Ann Anat. 2005 Nov;187(5-6):473-85
pubmed: 16320827
N Engl J Med. 2006 Feb 23;354(8):841-8
pubmed: 16495396
In Vitro Cell Dev Biol Anim. 2006 May-Jun;42(5-6):159-67
pubmed: 16848636
Biomaterials. 2007 Oct;28(30):4480-7
pubmed: 17629939
Biomed Mater Eng. 2007;17(5):269-76
pubmed: 17851169
J Tissue Eng Regen Med. 2008 Jan;2(1):14-21
pubmed: 18265427
Clin Orthop Relat Res. 2009 Jan;467(1):267-72
pubmed: 18709427
Biomed Mater. 2009 Apr;4(2):025006
pubmed: 19258698
Arthritis Res Ther. 2009;11(3):227
pubmed: 19519925
Osteoarthritis Cartilage. 2010 Nov;18(11):1509-17
pubmed: 20813194
J Orthop Res. 2010 Dec;28(12):1576-85
pubmed: 20973060
Biomaterials. 2011 Sep;32(25):5810-8
pubmed: 21592563
Osteoarthritis Cartilage. 2011 Oct;19(10):1219-27
pubmed: 21820068
Knee Surg Sports Traumatol Arthrosc. 2013 Feb;21(2):485-93
pubmed: 22488013
Am J Sports Med. 2013 Jan;41(1):95-100
pubmed: 23104612
Z Orthop Unfall. 2013 Feb;151(1):38-47
pubmed: 23423589
Am J Sports Med. 2014 Jan;42(1):59-69
pubmed: 24197614
J Orthop Res. 2014 Nov;32(11):1495-502
pubmed: 25088008
Knee Surg Sports Traumatol Arthrosc. 2015 Jan;23(1):104-11
pubmed: 25377190
Eur J Med Res. 2014 Nov 29;19:65
pubmed: 25432384
Cartilage. 2015 Jul;6(3):156-65
pubmed: 26175861
Biomaterials. 2017 Aug;137:37-48
pubmed: 28528301
Med Biol Eng Comput. 2018 Apr;56(4):657-669
pubmed: 28849317
Eur J Med Res. 2018 Jan 5;23(1):1
pubmed: 29304843
Cell J. 2018 Apr;20(1):53-60
pubmed: 29308619
Int J Mol Sci. 2018 Aug 03;19(8):null
pubmed: 30081513
N Engl J Med. 1994 Oct 6;331(14):889-95
pubmed: 8078550
Acta Orthop Scand. 1998 Feb;69(1):56-62
pubmed: 9524520