Glycolic acid as the final irrigant in endodontics: Mechanical and cytotoxic effects.
Citric acid
EDTA
Endodontics
Glycolic acid
Smear layer
Journal
Materials science & engineering. C, Materials for biological applications
ISSN: 1873-0191
Titre abrégé: Mater Sci Eng C Mater Biol Appl
Pays: Netherlands
ID NLM: 101484109
Informations de publication
Date de publication:
Jul 2019
Jul 2019
Historique:
received:
10
01
2019
revised:
19
02
2019
accepted:
04
03
2019
entrez:
6
4
2019
pubmed:
6
4
2019
medline:
9
8
2019
Statut:
ppublish
Résumé
The aim of this study was to investigate the effects of glycolic acid (GA) on the microhardness, roughness, dentin mineral content distribution; smear layer removal and cytotoxicity. One hundred human teeth were randomly divided into six groups: distilled water (control group), 17% EDTA, 10% citric acid (CA), 5% GA, 10% GA, and, 17% GA. Microhardness and roughness were measured in the canal lumen. Scanning electron microscopy (SEM) images (2000×) for smear layer removal evaluation; energy dispersive X-ray spectroscopy (EDS) for chemical analysis. Cell viability assay was made on fibroblast cells. The lowest microhardness and higher roughness were observed for 17% GA. GA showed the ability to remove the smear layer to a similar level as EDTA and CA, with no statistical difference between the concentrations used. GA and CA were cytotoxic in a dose-dependent manner. GA showed potential as an endodontic agent for final irrigation in root canal terapies.
Identifiants
pubmed: 30948068
pii: S0928-4931(19)30117-1
doi: 10.1016/j.msec.2019.03.016
pii:
doi:
Substances chimiques
Glycolates
0
Root Canal Irrigants
0
glycolic acid
0WT12SX38S
Types de publication
Journal Article
Langues
eng
Pagination
323-329Informations de copyright
Copyright © 2019 Elsevier B.V. All rights reserved.