A TetR-family transcription factor regulates fatty acid metabolism in the archaeal model organism Sulfolobus acidocaldarius.

Bacterial Proteins / genetics DNA / metabolism Fatty Acids / metabolism Gene Expression Regulation, Bacterial Sulfolobus acidocaldarius / genetics Transcription Factors / genetics

Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
04 04 2019
Historique:
received: 08 01 2018
accepted: 12 03 2019
entrez: 6 4 2019
pubmed: 6 4 2019
medline: 2 5 2019
Statut: epublish

Résumé

Fatty acid metabolism and its regulation are known to play important roles in bacteria and eukaryotes. By contrast, although certain archaea appear to metabolize fatty acids, the regulation of the underlying pathways in these organisms remains unclear. Here, we show that a TetR-family transcriptional regulator (FadR

Identifiants

DOI: 10.1038/s41467-019-09479-1 PMID: 30948713 PMC: PMC6449355
pubmed: 30948713
doi: 10.1038/s41467-019-09479-1
pii: 10.1038/s41467-019-09479-1
pmc: PMC6449355
doi:

Substances chimiques

Bacterial Proteins 0
Fatty Acids 0
Transcription Factors 0
DNA 9007-49-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1542

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Auteurs

Kun Wang (K)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius v. 20C, SE-10691, Stockholm, Sweden.

David Sybers (D)

Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

Hassan Ramadan Maklad (HR)

Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

Liesbeth Lemmens (L)

Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

Charlotte Lewyllie (C)

Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.
Laboratory of Cell Genetics, Department of Biology, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium.

Xiaoxiao Zhou (X)

Molekulare Enzymtechnologie und Biochemie, Biofilm Centre, ZWU, Fakultät für Chemie, Universität Duisburg-Essen, Universitätsstr. 2, 45117, Essen, Germany.

Frank Schult (F)

Molekulare Enzymtechnologie und Biochemie, Biofilm Centre, ZWU, Fakultät für Chemie, Universität Duisburg-Essen, Universitätsstr. 2, 45117, Essen, Germany.

Christopher Bräsen (C)

Molekulare Enzymtechnologie und Biochemie, Biofilm Centre, ZWU, Fakultät für Chemie, Universität Duisburg-Essen, Universitätsstr. 2, 45117, Essen, Germany.

Bettina Siebers (B)

Molekulare Enzymtechnologie und Biochemie, Biofilm Centre, ZWU, Fakultät für Chemie, Universität Duisburg-Essen, Universitätsstr. 2, 45117, Essen, Germany.

Karin Valegård (K)

Molecular Biophysics, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden.

Ann-Christin Lindås (AC)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Svante Arrhenius v. 20C, SE-10691, Stockholm, Sweden. Ann.Christin.Lindas@su.se.

Eveline Peeters (E)

Research Group of Microbiology, Department of Bioengineering Sciences, Vrije Universiteit Brussel, Pleinlaan 2, B-1050, Brussels, Belgium. Eveline.Peeters@vub.be.

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Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › A TetR-family transcription factor regulates...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ADN › A TetR-family transcription factor regulates...
questionsmedicales.fr › Lipides › Acides gras › A TetR-family transcription factor regulates...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Régulation de l'expression des gènes bactériens › A TetR-family transcription factor regulates...
questionsmedicales.fr › Archéobactéries › Crenarchaeota › Sulfolobale › Sulfolobaceae › Sulfolobus › Sulfolobus acidocaldarius › A TetR-family transcription factor regulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Facteurs de transcription › A TetR-family transcription factor regulates...