Bladder cancer demographics and outcome data from 2013 at a tertiary cancer hospital in India.


Journal

Indian journal of cancer
ISSN: 1998-4774
Titre abrégé: Indian J Cancer
Pays: India
ID NLM: 0112040

Informations de publication

Date de publication:
Historique:
entrez: 6 4 2019
pubmed: 6 4 2019
medline: 3 8 2019
Statut: ppublish

Résumé

Bladder cancer (BCa) is the ninth most common cancer accounting for 3.9% of all cancer cases as per the Indian Cancer Registry data. There is a scarcity of data on urinary Bca from India. The aim of this study was to know demographic background, stage distribution, utilization of various treatment modalities, and oncological outcome in Indian patients presenting with bladder cancer to a tertiary care cancer center in Mumbai. We performed a retrospective audit of all patients registered as urinary BCa in our hospital from January 1, 2013 to December 31, 2013. Electronic medical records of these patients were checked for most of the information gathered. Median age of patients at presentation was 59 years with a range of 18-88 years. There were 84% male and 16% female patients. Forty seven percent of patients had nonmuscle invasive bladder cancer (NMIBC), 36% had muscle invasive bladder cancer and locally advanced disease, and 17% had metastatic disease. Eight patients were treated with trimodality bladder preservation protocol. Recurrence was seen in 38 (22.6%) patients with NMIBC. Out of them. 44.7% and 55.3% were in low- and high-grade tumors, respectively. Overall survival and disease-free survival estimated for 3 years were 63% and 57%, respectively. Bladder cancer has a varied spectrum of presentation. Bladder cancer patients presenting to our hospital generally have a higher stage and grade of disease compared with that in the west.

Sections du résumé

BACKGROUND BACKGROUND
Bladder cancer (BCa) is the ninth most common cancer accounting for 3.9% of all cancer cases as per the Indian Cancer Registry data. There is a scarcity of data on urinary Bca from India.
AIM OBJECTIVE
The aim of this study was to know demographic background, stage distribution, utilization of various treatment modalities, and oncological outcome in Indian patients presenting with bladder cancer to a tertiary care cancer center in Mumbai.
METHODOLOGY METHODS
We performed a retrospective audit of all patients registered as urinary BCa in our hospital from January 1, 2013 to December 31, 2013. Electronic medical records of these patients were checked for most of the information gathered.
RESULTS RESULTS
Median age of patients at presentation was 59 years with a range of 18-88 years. There were 84% male and 16% female patients. Forty seven percent of patients had nonmuscle invasive bladder cancer (NMIBC), 36% had muscle invasive bladder cancer and locally advanced disease, and 17% had metastatic disease. Eight patients were treated with trimodality bladder preservation protocol. Recurrence was seen in 38 (22.6%) patients with NMIBC. Out of them. 44.7% and 55.3% were in low- and high-grade tumors, respectively. Overall survival and disease-free survival estimated for 3 years were 63% and 57%, respectively.
CONCLUSION CONCLUSIONS
Bladder cancer has a varied spectrum of presentation. Bladder cancer patients presenting to our hospital generally have a higher stage and grade of disease compared with that in the west.

Identifiants

pubmed: 30950446
pii: IndianJournalofCancer_2019_56_1_54_255481
doi: 10.4103/ijc.IJC_351_18
doi:

Types de publication

Journal Article

Langues

eng

Pagination

54-58

Déclaration de conflit d'intérêts

There are no conflicts of interest.

Auteurs

Gagan Prakash (G)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Mahendra Pal (M)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

K Odaiyappan (K)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Rajesh Shinde (R)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Jeeban Mishra (J)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Devendra Jalde (D)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Barath Rajkumar (B)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Kumar Prabhash (K)

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Amit Joshi (A)

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Vanita Noronha (V)

Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Vedang Murthy (V)

Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Rahul Krishnatry (R)

Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Sangeeta Desai (S)

Department of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Santosh Menon (S)

Department of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Nilesh Sable (N)

Department of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Palak Popat (P)

Department of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Venkatesh Rangarajan (V)

Department of Nuclear Medicine, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Archi Agrawal (A)

Department of Nuclear Medicine, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Ganesh Bakshi (G)

Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.

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Classifications MeSH