Impact of salt taste dysfunction on interdialytic weight gain for hemodialysis patients; a cross-sectional study.
Hemodialysis
Interdialytic weight gain
Salt taste dysfunction
Journal
BMC nephrology
ISSN: 1471-2369
Titre abrégé: BMC Nephrol
Pays: England
ID NLM: 100967793
Informations de publication
Date de publication:
05 04 2019
05 04 2019
Historique:
received:
14
09
2018
accepted:
27
03
2019
entrez:
7
4
2019
pubmed:
7
4
2019
medline:
10
5
2020
Statut:
epublish
Résumé
Little is known about salt taste dysfunction among hemodialysis (HD) patients. This study aimed to elucidate the prevalence of salt taste dysfunction and its relationship with interdialytic weight gain (IDWG) among HD patients. A single-center cross-sectional study involving 99 maintenance HD patients was conducted in September 2015. Salt taste threshold was measured using a salt-impregnated test strip. Salt taste dysfunction was defined as a recognition threshold of ≥0.8%. IDWG was calculated as the mean value of weight gain at the beginning of each week during a 1-month period before the taste test. We performed a multivariate analysis using the standard linear regression model to investigate the association between salt taste dysfunction and IDWG. Among the 99 participants, 42% had a recognition threshold of 0.6%, whereas 38% had a recognition threshold of ≥1.6%. Overall, the prevalence of salt taste dysfunction was 58%. The mean (±SD) IDWG was 4.9% (±1.7%), and there was no significant difference in IDWG between the two groups with (4.9%) and without (4.8%) salt taste dysfunction (P = 0.90). A multivariate analysis indicated that salt taste dysfunction is not significantly associated with IDWG (mean difference = 0.06; 95% confidence interval = - 0.27 to 0.40). The prevalence of salt taste dysfunction was very high among HD patients who had a unique distribution of salt taste recognition thresholds with two peaks. We found no significant association between salt taste dysfunction and IDWG.
Sections du résumé
BACKGROUND
Little is known about salt taste dysfunction among hemodialysis (HD) patients. This study aimed to elucidate the prevalence of salt taste dysfunction and its relationship with interdialytic weight gain (IDWG) among HD patients.
METHODS
A single-center cross-sectional study involving 99 maintenance HD patients was conducted in September 2015. Salt taste threshold was measured using a salt-impregnated test strip. Salt taste dysfunction was defined as a recognition threshold of ≥0.8%. IDWG was calculated as the mean value of weight gain at the beginning of each week during a 1-month period before the taste test. We performed a multivariate analysis using the standard linear regression model to investigate the association between salt taste dysfunction and IDWG.
RESULTS
Among the 99 participants, 42% had a recognition threshold of 0.6%, whereas 38% had a recognition threshold of ≥1.6%. Overall, the prevalence of salt taste dysfunction was 58%. The mean (±SD) IDWG was 4.9% (±1.7%), and there was no significant difference in IDWG between the two groups with (4.9%) and without (4.8%) salt taste dysfunction (P = 0.90). A multivariate analysis indicated that salt taste dysfunction is not significantly associated with IDWG (mean difference = 0.06; 95% confidence interval = - 0.27 to 0.40).
CONCLUSIONS
The prevalence of salt taste dysfunction was very high among HD patients who had a unique distribution of salt taste recognition thresholds with two peaks. We found no significant association between salt taste dysfunction and IDWG.
Identifiants
pubmed: 30953463
doi: 10.1186/s12882-019-1312-3
pii: 10.1186/s12882-019-1312-3
pmc: PMC6451217
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
121Subventions
Organisme : the Institute for Health Outcomes and Process Evaluation research (www.i-hope.jp)
ID : KJ14-02
Pays : International
Références
Nephrol Dial Transplant. 2013 Apr;28(4):797-802
pubmed: 23129821
Kidney Int. 2012 Jul;82(2):204-11
pubmed: 22418981
Nephrol Dial Transplant. 2000 Dec;15(12):2063
pubmed: 11096160
J Am Diet Assoc. 1984 Oct;84(10):1203-6, 1209
pubmed: 6481044
Acta Otorhinolaryngol Belg. 1985;39(5):822-31
pubmed: 4096222
Nephron. 1980;26(4):163-70
pubmed: 7432578
Kidney Int. 1979 Jan;15(1):49-53
pubmed: 491397
J Ren Nutr. 2013 Jul;23(4):288-295.e1
pubmed: 23046735
J Ren Nutr. 2002 Jan;12(1):38-41
pubmed: 11823992
Nephrol Dial Transplant. 2009 Mar;24(3):956-62
pubmed: 19004849
Kidney Int. 2009 Sep;76(6):638-43
pubmed: 19516246
J Nutr. 1999 Jan;129(1):122-5
pubmed: 9915887
Am J Kidney Dis. 1998 Jul;32(1):139-45
pubmed: 9669435
Clin Nephrol. 1996 Mar;45(3):169-74
pubmed: 8706357
ORL J Otorhinolaryngol Relat Spec. 1996 Sep-Oct;58(5):258-61
pubmed: 8936475
Semin Dial. 2010 Jul-Aug;23(4):415-21
pubmed: 20557489
Eur J Med. 1992 Jul-Aug;1(4):208-14
pubmed: 1341446
Pharmacol Biochem Behav. 1984 Aug;21(2):203-8
pubmed: 6483932
Am J Clin Nutr. 1980 Jul;33(7):1517-21
pubmed: 6772011
Circulation. 2009 Feb 10;119(5):671-9
pubmed: 19171851
JAMA. 1997 Oct 22-29;278(16):1357-62
pubmed: 9343468
Appetite. 1992 Apr;18(2):111-9
pubmed: 1610160