Left atrial appendage occlusion in patients older than 85 years. Safety and efficacy in the EWOLUTION registry.


Journal

Revista espanola de cardiologia (English ed.)
ISSN: 1885-5857
Titre abrégé: Rev Esp Cardiol (Engl Ed)
Pays: Spain
ID NLM: 101587954

Informations de publication

Date de publication:
Jan 2020
Historique:
received: 12 11 2018
accepted: 14 02 2019
pubmed: 9 4 2019
medline: 23 1 2020
entrez: 9 4 2019
Statut: ppublish

Résumé

Elderly patients with atrial fibrillation are at greater risk of both cardioembolic events and major bleeding than younger patients. Left atrial appendage occlusion (LAAO) could be an attractive alternative for these patients, but there are limited data on outcomes with LAAO in patients ≥ 85 years old. The aim of the present study was to assess the safety and efficacy of LAAO in patients ≥ 85 years old. A total of 1025 patients included in the EWOLUTION registry who underwent LAAO were analyzed and 84 patients ≥ 85 years old were identified and compared with the younger cohort. Patients ≥ 85 years old had higher estimated stroke and hemorrhagic risks than younger patients (CHA LAAO in patients ≥ 85 years is safe and effective even though these patients are at high risk for embolic and hemorrhagic events. LAAO may be a reasonable alternative to oral anticoagulation in these patients.

Identifiants

pubmed: 30956034
pii: S1885-5857(19)30047-7
doi: 10.1016/j.rec.2019.02.008
pii:
doi:

Types de publication

Comparative Study Journal Article Multicenter Study

Langues

eng spa

Sous-ensembles de citation

IM

Pagination

21-27

Informations de copyright

Copyright © 2019 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.

Auteurs

Ignacio Cruz-González (I)

Servicio de Cardiología, Hospital Universitario de Salamanca, Instituto de Investigación Biomédica de Salamanca (IBSAL), Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBER-CV), Salamanca, Spain. Electronic address: cruzgonzalez.ignacio@gmail.com.

Hueseyin Ince (H)

Kardiologie, Vivantes Klinikum Am Urban and Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Stephan Kische (S)

Kardiologie, Vivantes Klinikum im Friedrichshain, Berlin, Germany.

Thomas Schmitz (T)

Kardiologie, Elisabeth Krankenhaus Essen, Essen, Germany.

Boris Schmidt (B)

Kardiologie, Cardioangiologisches Centrum Bethanien (CCB), Frankfurt Am Main, Germany.

Tommaso Gori (T)

Kardiologie, Universitätsmedizin Mainz und DZHK Standort Rhein-Main, Mainz, Germany.

David Foley (D)

Cardiology Deparment, Beaumont Hospital, Dublin, Ireland.

Tom de Potter (T)

Cardiologie, Onze Lieve Vrouw Ziekenhuis, Aalst, Belgium.

Wladimir Tschishow (W)

Kardiologie, Evangelisches Krankenhaus Bielefeld, Bielefeld, Germany.

Elisa Vireca (E)

Boston Scientific, Diegem, Belgium.

Kenneth Stein (K)

Boston Scientific Corp, Minneapolis, Minessota, United States.

Lucas V Boersma (LV)

Cardiologie, St Antonius Hospital, Nieuwegein, The Netherlands.

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Classifications MeSH